Martin Gotthardt

TL;DR: This review aims to provide nuclear medicine specialists and clinicians with the relevant information on rational and efficient use of nuclear medicine imaging techniques in the assessment of patients with osteomyelitis, infected vascular prostheses, metastatic infectious disease, rheumatoid arthritis, vasculitis, inflammatory bowel disease, sarcoidosis, and fever of unknown origin.

TL;DR: SPECT/computed tomography (CT) with (111)In-WBC combined with (99m)Tc-MDP or ( 99m) tc-sulfur colloid seems to be the best imaging technique for diagnosis of bone and joint infections.

TL;DR: In this murine tumour model optimal targeting of the GLP-1R expressing tumour was obtained at exendin doses ≤0.1 µg and in vivo targeting was investigated in BALB/c nude mice with subcutaneous INS-1 tumours.

TL;DR: Megalin is involved in the renal reabsorption of radiolabelled octreotide, octreotate, exendin, neurotensin and minigastrin, and knowledge may help in the design of strategies to reduce this re absorption and the resulting nephrotoxicity in peptide receptor radionuclide therapy, enabling more effective therapy.

TL;DR: This review provides an overview of past, current, and promising newly developed radiopharmaceuticals and describes the role and recent advances of scintigraphic techniques to measure cardiotoxicity.