M
Martine Billard
Researcher at French Institute of Health and Medical Research
Publications - 31
Citations - 3377
Martine Billard is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Antigen & Tetraspanin. The author has an hindex of 22, co-authored 31 publications receiving 3245 citations. Previous affiliations of Martine Billard include University of Michigan & Université Paris-Saclay.
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Journal ArticleDOI
CD9, CD63, CD81, and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins
Eric Rubinstein,François Le Naour,Cécile Lagaudrière-Gesbert,Martine Billard,Hélène Conjeaud,Claude Boucheix +5 more
TL;DR: The existence of a tetraspan network which, by connecting several molecules, may organize the positioning of cell surface proteins and play a role in signal transduction, cell adhesion, and motility is suggested.
Journal ArticleDOI
Differential stability of tetraspanin/tetraspanin interactions: role of palmitoylation
Stéphanie Charrin,Serge Manié,Michael Oualid,Martine Billard,Claude Boucheix,Eric Rubinstein +5 more
TL;DR: The palmitoylation of CD9 did not influence the partition in detergent‐resistant membranes but contributed to the interaction with CD81 and CD53, and the resistance of the CD9/CD81 interaction to EDTA, which disrupts other tetraspanin/tetraspAnin interactions, was entirely dependent on palmitoyslation.
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The major CD9 and CD81 molecular partner. Identification and characterization of the complexes.
Stéphanie Charrin,François Le Naour,Michael Oualid,Martine Billard,Gilbert Faure,Samir M. Hanash,Claude Boucheix,Eric Rubinstein +7 more
TL;DR: The identification of a protein strongly linked to the tetraspanin web and the production of a specific monoclonal antibody will help to further characterize the role of this “web” under physiological and pathological conditions.
Journal ArticleDOI
Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions.
Serru,Le Naour F,Martine Billard,David O. Azorsa,François Lanza,Claude Boucheix,Eric Rubinstein +6 more
TL;DR: It is shown that another classical mild detergent, digitonin, dissociated most of these associated molecules, including integrins, from the tetraspans CD9, CD37, CD53, CD63, CD82, Co-029, Talla-1 and NAG-2, and a new anti-CD151 monoclonal antibody (mAb) was shown to have a restricted pattern of expression.
Journal ArticleDOI
A physical and functional link between cholesterol and tetraspanins
Stéphanie Charrin,Serge Manié,Christoph Thiele,Martine Billard,Denis Gerlier,Claude Boucheix,Eric Rubinstein +6 more
TL;DR: It is shown that tetraspanins interact with cholesterol as indicated by the precipitation by digitonin, a cholesterol‐precipitating reagent, and the labeling of the tetrascanins CD9, CD81 and CD82 with a photoactivatable cholesterol in vivo.