M
Mary Bownes
Researcher at University of Edinburgh
Publications - 112
Citations - 5755
Mary Bownes is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Drosophila melanogaster & Yolk. The author has an hindex of 39, co-authored 112 publications receiving 5494 citations.
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Journal ArticleDOI
3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.
Dario R. Alessi,Maria Deak,Antonio Casamayor,F. Barry Caudwell,Nick Morrice,David Norman,Piers R. J. Gaffney,Colin B. Reese,Colin N. MacDougall,Diane Harbison,Alan Ashworth,Mary Bownes +11 more
TL;DR: Human PDK1 is homologous to the Drosophila protein kinase DSTPK61, which has been implicated in the regulation of sex differentiation, oogenesis and spermatogenesis and is likely to mediate the activation of PKB by insulin or growth factors.
Journal ArticleDOI
Staging the metamorphosis of Drosophila melanogaster
S. Paul Bainbridge,Mary Bownes +1 more
TL;DR: A sequence of 51 visible changes is described during the course of metamorphosis in Drosophila melanogaster, and a series of 24 convenient stages is defined for use in the experimental analysis and exploitation of this part of the insect life cycle.
Journal ArticleDOI
Control of oocyte maturation in sexually mature Drosophila females.
TL;DR: It is concluded that juvenile hormone is a downstream component in the Sex-Peptide response cascade and acts by stimulating vitellogenic oocyte progression and inhibiting apoptosis and the balance of these hormones in the hemolymph regulates whether oocytes will progress through the control point at stage 9 or undergo apoptosis.
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Two signalling pathways specify localised expression of the Broad-Complex in Drosophila eggshell patterning and morphogenesis
Wu-Min Deng,Mary Bownes +1 more
TL;DR: It is shown that the Broad-Complex, a gene encoding zinc-finger transcription factors, is essential for the morphogenesis of dorsal appendages and is expressed in a bilaterally symmetrical pattern in the lateral-dorsal-anterior follicle cells during late oogenesis.
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The roles of juvenile hormone, ecdysone and the ovary in the control of Drosophila vitellogenesis
TL;DR: It is shown that flies without ovaries have normal levels of free ecysteroids after 2 days suggesting that the ovaries do not produce substantial quantities of free ecdysteroids continuously in the adult for use in regulating vitellogenesis, however, they probably do contribute to the whole body titre in mature flies since titres do become less in ovary-less flies at 3 days.