M
Mary Francis Pochran
Researcher at University of Maryland Marlene and Stewart Greenebaum Cancer Center
Publications - 1
Citations - 322
Mary Francis Pochran is an academic researcher from University of Maryland Marlene and Stewart Greenebaum Cancer Center. The author has contributed to research in topics: Vaccination & Hematopoietic stem cell transplantation. The author has an hindex of 1, co-authored 1 publications receiving 310 citations.
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Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer
Aaron P. Rapoport,Edward A. Stadtmauer,Nicole A. Aqui,Ashraf Badros,Julio Cotte,Lisa Chrisley,Elizabeth Veloso,Zhaohui Zheng,Sandra Westphal,Rebecca Mair,Nina Chi,Bashi Ratterree,Mary Francis Pochran,Sabrina Natt,Joanne Hinkle,C Sickles,Ambika Sohal,Kathleen Ruehle,Christian Lynch,Lei Zhang,David L. Porter,Selina M. Luger,Chuanfa Guo,Hong-Bin Fang,William C. Blackwelder,Kim Hankey,Dean L. Mann,Robert R. Edelman,Carl E. Frasch,Bruce L. Levine,Alan S. Cross,Carl H. June +31 more
TL;DR: Combination immunotherapy consisting of a single early post-transplant infusion of in vivo vaccine-primed and ex vivo costimulated autologous T cells followed by post-Transplant booster immunizations improved the severe immunodeficiency associated with high-dose chemotherapy and led to the induction of clinically relevant immunity in adults within a month after transplantation.