D
Dean L. Mann
Researcher at University of Maryland, Baltimore
Publications - 212
Citations - 16056
Dean L. Mann is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Antigen & Human leukocyte antigen. The author has an hindex of 65, co-authored 210 publications receiving 15746 citations. Previous affiliations of Dean L. Mann include University of Pennsylvania & University of Maryland Marlene and Stewart Greenebaum Cancer Center.
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Journal ArticleDOI
Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS)
Robert C. Gallo,Prem S. Sarin,Edward P. Gelmann,Marjorie Robert-Guroff,Ersell Richardson,V. S. Kalyanaraman,Dean L. Mann,Gurdip D. Sidhu,Rosalyn E. Stahl,Susan Zolla-Pazner,Jacque Leibowitch,Mikulas Popovic +11 more
TL;DR: Whether or not HTLV-I or other retroviruses of this family with T-cell tropism cause AIDS, it is possible that patients from whom the virus can be isolated can also transmit it to others.
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Influence of combinations of human major histocompatibility complex genes on the course of HIV–1 infection
Richard A. Kaslow,Mary Carrington,Raymond J. Apple,Lawrence P. Park,Alvaro Muñoz,A. J. Saah,James J. Goedert,Cheryl A. Winkler,Stephen J. O'Brien,Charles R. Rinaldo,Roger Detels,William A. Blattner,John P. Phair,Henry A. Erlich,Dean L. Mann +14 more
TL;DR: An HLA profile was produced that predicted time from HIV–1 infection to the onset of AIDS and support current theory about control of antigen processing by HLA genes and have implications for immunopathogenesis of HIV-1 and other infections.
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Cellular proteins bound to immunodeficiency viruses: implications for pathogenesis and vaccines.
Larry O. Arthur,Julian W. Bess,Raymond C. Sowder,Raoul E. Benveniste,Dean L. Mann,Jean-Claude Chermann,Louis E. Henderson +6 more
TL;DR: The specific, selective association of these cellular proteins in a physiologically relevant manner has major implications for the understanding of the infection process and the pathogenesis of immunodeficiency viruses and should be considered in the design of vaccines.
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Isolation and Transmission of Human Retrovirus (Human T-Cell Leukemia Virus)
Mikulas Popovic,Prem S. Sarin,M Robert-Gurroff,V. S. Kalyanaraman,Dean L. Mann,Jun Minowada,Robert C. Gallo +6 more
TL;DR: Nine new isolates of human T-cell leukemia-lymphoma virus (HTLV) were obtained from cells of seven patients with malignancies of mature T cells and from two clinically normal relatives of a T- cell leukemia patient.
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A Prospective Study of Human Immunodeficiency Virus Type 1 Infection and the Development of AIDS in Subjects with Hemophilia
James J. Goedert,Craig M. Kessler,Louis M. Aledort,Robert J. Biggar,W. Abe Andes,Gilbert C. White,James E. Drummond,Kampala Vaidya,Dean L. Mann,M. Elaine Eyster,Margaret V. Ragni,Michael M. Lederman,Alan R. Cohen,Gordon L. Bray,Philip S. Rosenberg,Robert M. Friedman,Margaret W. Hilgartner,William A. Blattner,Barbara Kroner,Mitchell H. Gail +19 more
TL;DR: The findings not only demonstrate that the risk of AIDS is related directly to age but also suggest that older adults are disproportionately affected during the earlier phases of HIV disease, that adolescents may have a low replication rate of HIV, and that children and adolescents may tolerate severe immunodeficiency better because they have fewer other infections or because of some unmeasured, age-dependent cofactor or immune alteration in the later phase of HIV Disease.