M
Mary K. McCarthy
Researcher at University of Colorado Denver
Publications - 35
Citations - 755
Mary K. McCarthy is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Immune system & Virus. The author has an hindex of 12, co-authored 32 publications receiving 469 citations. Previous affiliations of Mary K. McCarthy include Anschutz Medical Campus & University of Michigan.
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Journal ArticleDOI
The immunoproteasome and viral infection: a complex regulator of inflammation
TL;DR: A better understanding of the role of the immunoproteasome in different cell types, tissues, and hosts has the potential to improve vaccine design and facilitate the development of effective treatment strategies for viral infections.
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A New SARS CoV-2 Dual Purpose Serology Test: Highly Accurate Infection Tracing and Neutralizing Antibody Response Detection.
Sean C. Taylor,Beth Hurst,Carmen L. Charlton,Carmen L. Charlton,Ashley Bailey,Jamil N. Kanji,Jamil N. Kanji,Mary K. McCarthy,Thomas E. Morrison,Leah Huey,Leah Huey,Kyle Annen,Kyle Annen,Melkon G DomBourian,Melkon G DomBourian,Vijaya Knight,Vijaya Knight +16 more
TL;DR: In this article, a surrogate virus neutralization test (sVNT) was proposed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serology tests.
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Type 1 IFN and PD-L1 Coordinate Lymphatic Endothelial Cell Expansion and Contraction during an Inflammatory Immune Response
Erin D. Lucas,Jeffrey M. Finlon,Matthew A. Burchill,Mary K. McCarthy,Thomas E. Morrison,Tonya M. Colpitts,Beth A. Jirón Tamburini +6 more
TL;DR: A direct role for both type 1 IFN and PD-L1 in inhibiting LEC division and in promoting LEC survival is demonstrated and reveals a novel mechanism for the coordination of type 1IFN andPD-L 1 in manipulating LEC expansion and survival during an inflammatory immune response.
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IL-17 contributes to neutrophil recruitment but not to control of viral replication during acute mouse adenovirus type 1 respiratory infection.
TL;DR: In this article, the authors used mouse adenovirus type 1 (MAV-1) to determine contributions of IL-17 to pathogenesis, and showed robust Th17 responses were not essential for control of virus infection or for virus-induced pulmonary inflammation.
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Eicosanoids and respiratory viral infection: coordinators of inflammation and potential therapeutic targets.
TL;DR: Lung inflammation induced by infection with common respiratory pathogens is accompanied by increased lung production of prostaglandins and leukotrienes, lipid mediators with a wide range of effects on host immune function that serve as appealing therapeutic targets for disease caused by respiratory viral infection.