M
Mary M. Lee
Researcher at Thomas Jefferson University
Publications - 117
Citations - 5161
Mary M. Lee is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Environmental exposure & Leydig cell. The author has an hindex of 38, co-authored 111 publications receiving 4747 citations. Previous affiliations of Mary M. Lee include Harvard University & Cornell University.
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Journal ArticleDOI
Mullerian inhibiting substance in humans: normal levels from infancy to adulthood
Mary M. Lee,Patricia K. Donahoe,Tomonobu Hasegawa,Bernard L. Silverman,Gretchen B. Crist,Sharon Best,Yukihiro Hasegawa,Richard A. Noto,David A. Schoenfeld,David T. MacLaughlin +9 more
TL;DR: Data reveal an easily discernible sexually dimorphic pattern of expression of MIS and confirm that MIS can be used as a testis-specific marker during infancy and early childhood and facilitate the use of MIS in the management of gonadal disorders.
Journal ArticleDOI
Mullerian Inhibiting Substance: A Gonadal Hormone with Multiple Functions
Mary M. Lee,Patricia K. Donahoe +1 more
TL;DR: The current understanding of the biology and multiple functions of MIS including its activation, regulation, and mechanism of action are summarized and areas of interest in ongoing research are discussed.
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Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men.
Mark L. Hartman,Johannes D. Veldhuis,Michael L. Johnson,Mary M. Lee,K. G. M. M. Alberti,Eugene Samojlik,Michael O. Thorner +6 more
TL;DR: The present data suggest that starvation-induced enhancement of GH secretion is mediated by an increased frequency of GHRH release, and longer and more pronounced periods of somatostatin withdrawal.
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Measurements of Serum Müllerian Inhibiting Substance in the Evaluation of Children with Nonpalpable Gonads
Mary M. Lee,Patricia K. Donahoe,Bernard L. Silverman,Tomonobu Hasegawa,Yukihiro Hasegawa,Michael L. Gustafson,Yuchiao Chang,David T. MacLaughlin +7 more
TL;DR: Measurements of serum mullerian inhibiting substance can be used to determine testicular status in prepubertal children with nonpalpable gonads, thus differentiating anorchia from undescended testes in boys with bilateral cryptorchidism and serving as a measure of testicular integrity in children with intersexual anomalies.
Journal ArticleDOI
Alterations in the Pulsatile Mode of Growth Hormone Release in Men and Women with Insulin-Dependent Diabetes Mellitus
Christopher M. Asplin,A. C. S. Faria,Elisabeth Carlsen,Veronica A. Vaccaro,Richard E. Barr,Ali Iranmanesh,Mary M. Lee,Johannes D. Veldhuis,William S. Evans +8 more
TL;DR: The altered frequency of GH pulses together with enhanced interpulse GH concentrations and an amplified circadian GH rhythm are compatible with hypothalamic dysfunction associated with dysregulation of somatostatin and/or GHRH secretion.