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Ali Iranmanesh

Researcher at Veterans Health Administration

Publications -  152
Citations -  10432

Ali Iranmanesh is an academic researcher from Veterans Health Administration. The author has contributed to research in topics: Growth hormone secretion & Luteinizing hormone. The author has an hindex of 54, co-authored 148 publications receiving 10076 citations. Previous affiliations of Ali Iranmanesh include University of Virginia & Salem VA Medical Center.

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Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men

TL;DR: It is concluded that T gel replacement improved sexual function and mood, increased lean mass and muscle strength (principally in the legs), and decreased fat mass in hypogonadal men with less skin irritation and discontinuation compared with the recommended dose of the permeation-enhanced T patch.
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Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men.

TL;DR: It is concluded that continued application of AndroGel resulted in beneficial effects similar to those with injectables and other transdermal preparations and monitoring for prostatic disease and assessment for erythrocytosis are strongly advised to reduce the risk of adverse events with T treatment of hypogonadal men.
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Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man.

TL;DR: It is concluded that obese men harbor a double defect in GH dynamics involving both GH secretion and clearance, and that the severity of the GH secretory deficiency is proportionate to the degree of obesity.