M
Mary Savoye
Researcher at Yale University
Publications - 49
Citations - 9654
Mary Savoye is an academic researcher from Yale University. The author has contributed to research in topics: Insulin resistance & Obesity. The author has an hindex of 27, co-authored 45 publications receiving 9052 citations.
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Journal ArticleDOI
Obesity and the metabolic syndrome in children and adolescents.
Ram Weiss,James Dziura,Tania S. Burgert,William V. Tamborlane,Sara E. Taksali,Catherine W. Yeckel,Karin Allen,Melinda Lopes,Mary Savoye,John C. Morrison,Robert S. Sherwin,Sonia Caprio +11 more
TL;DR: The prevalence of the metabolic syndrome is high among obese children and adolescents, and it increases with worsening obesity, particularly in severely obese youngsters.
Journal ArticleDOI
Prevalence of Impaired Glucose Tolerance among Children and Adolescents with Marked Obesity
Ranjana Sinha,Gene Fisch,Barbara Teague,William V. Tamborlane,Bruna Banyas,Karin Allen,Mary Savoye,Vera Rieger,Sara E. Taksali,Gina Barbetta,Robert S. Sherwin,Sonia Caprio +11 more
TL;DR: Insulin resistance was greater in the affected cohort and was the best predictor of impaired glucose tolerance and Overt type 2 diabetes was linked to beta-cell failure.
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Effects of a weight management program on body composition and metabolic parameters in overweight children: a randomized controlled trial.
Mary Savoye,Melissa Shaw,James Dziura,William V. Tamborlane,Paulina Rose,Cindy Guandalini,Rachel Goldberg-Gell,Tania S. Burgert,Anna M. G. Cali,Ram Weiss,Sonia Caprio +10 more
TL;DR: The Bright Bodies weight management program had beneficial effects on body composition and insulin resistance in overweight children that were sustained up to 12 months.
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Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity.
Ranjana Sinha,Sylvie Dufour,Kitt Falk Petersen,Vincent Lebon,Staffan Enoksson,Yong-Zhan Ma,Mary Savoye,Douglas L. Rothman,Gerald I. Shulman,Sonia Caprio +9 more
TL;DR: A strong inverse correlation was found between IMCL and insulin sensitivity, which persisted and became even stronger after controlling for percent total body fat and abdominal subcutaneous fat mass, and suggest that these findings are not a consequence of aging but occur early in the natural course of obesity.
Journal ArticleDOI
Prediabetes in obese youth: a syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning.
Ram Weiss,Sylvie Dufour,Sara E. Taksali,William V. Tamborlane,K F Petersen,Riccardo C. Bonadonna,Linda Boselli,Gina Barbetta,Karin Allen,Francis Rife,Mary Savoye,James Dziura,Robert S. Sherwin,Gerald I. Shulman,Sonia Caprio +14 more
TL;DR: In obese children and adolescents with prediabetes, intramyocellular and intra-abdominal lipid accumulation is closely linked to the development of severe peripheral insulin resistance.