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Mary W. Brown

Researcher at University of Rochester Medical Center

Publications -  53
Citations -  15490

Mary W. Brown is an academic researcher from University of Rochester Medical Center. The author has contributed to research in topics: Multicenter Automatic Defibrillator Implantation Trial & Cardiac resynchronization therapy. The author has an hindex of 29, co-authored 48 publications receiving 14652 citations. Previous affiliations of Mary W. Brown include Columbia University & University of Rochester.

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Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction.

TL;DR: In patients with a prior myocardial infarction and advanced left ventricular dysfunction, prophylactic implantation of a defibrillator improves survival and should be considered as a recommended therapy.
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Reduction in Inappropriate Therapy and Mortality through ICD Programming

TL;DR: Programming of ICD therapies for tachyarrhythmias of 200 beats per minute or higher or with a prolonged delay in therapy at 170 beats perminute or higher, as compared with conventional programming, was associated with reductions in inappropriate therapy and all-cause mortality during long-term follow-up.
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Long-term clinical course of patients after termination of ventricular tachyarrhythmia by an implanted defibrillator

TL;DR: These patients are at increased risk for heart failure and nonsudden cardiac death after device termination of VT or VF and should receive special attention for the prevention and management of progressive left ventricular dysfunction during long-term follow-up.
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Analysis of mortality events in the multicenter automatic defibrillator implantation trial (MADIT-II)☆

TL;DR: The decrease in mortality with ICD therapy in MADIT-II is entirely due to a reduction inSCD, with similar reductions in SCD in a spectrum of subgroups stratified according to relevant baseline characteristics.