M
Masahiro Furuno
Researcher at Osaka University
Publications - 10
Citations - 118
Masahiro Furuno is an academic researcher from Osaka University. The author has contributed to research in topics: Metabolome & Gas chromatography–mass spectrometry. The author has an hindex of 5, co-authored 10 publications receiving 73 citations.
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Journal ArticleDOI
Hypoxanthine Secretion from Human Adipose Tissue and its Increase in Hypoxia
Hirofumi Nagao,Hitoshi Nishizawa,Yoshimitsu Tanaka,Tadafumi Fukata,Tsunekazu Mizushima,Masahiro Furuno,Takeshi Bamba,Takeshi Bamba,Yu Tsushima,Yuya Fujishima,Shunbun Kita,Tohru Funahashi,Norikazu Maeda,Masaki Mori,Eiichiro Fukusaki,Iichiro Shimomura +15 more
TL;DR: The production of uric acid in murine white adipose tissue (mWAT) was reported and that such production was augmented in obese mice, and this was analyzed in human WAT.
Journal ArticleDOI
Mechanistic study on the high-selectivity enantioseparation of amino acids using a chiral crown ether-bonded stationary phase and acidic, highly organic mobile phase by liquid chromatography/time-of-flight mass spectrometry.
TL;DR: The liquid chromatography/time-of-flight mass spectrometry method with the optimized MP enabled the determination of eighteen pairs of proteinogenic amino acid enantiomers within 10 min, and provided the following advantages: fast and highly reproducible separations under isocratic conditions, and high sensitivity and low backpressure using the MP with a high organic content.
Journal ArticleDOI
Fast enantiomeric separation of amino acids using liquid chromatography/mass spectrometry on a chiral crown ether stationary phase.
TL;DR: The results demonstrated the benefits of using shorter columns packed with smaller particles and the reduction of the extra-column band broadening for fast enantiomeric separation.
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Plasma metabolites associated with arterial stiffness in patients with type 2 diabetes
Naoto Katakami,Kazuo Omori,Naohiro Taya,Shoya Arakawa,Mitsuyoshi Takahara,Taka-aki Matsuoka,Hiroshi Tsugawa,Masahiro Furuno,Takeshi Bamba,Eiichiro Fukusaki,Iichiro Shimomura +10 more
TL;DR: The plasma levels of indoxyl sulfate were associated with arterial stiffness in Japanese patients with type 2 diabetes, and significant associations between the baPWV and Plasma levels of the other three metabolites were not confirmed.
Journal ArticleDOI
Identification of Plasma Inositol and Indoxyl Sulfate as Novel Biomarker Candidates for Atherosclerosis in Patients with Type 2 Diabetes. -Findings from Metabolome Analysis Using GC/MS.
Kazuo Omori,Naoto Katakami,Shoya Arakawa,Yuichi Yamamoto,Hiroyo Ninomiya,Mitsuyoshi Takahara,Taka-aki Matsuoka,Hiroshi Tsugawa,Masahiro Furuno,Takeshi Bamba,Eiichiro Fukusaki,Iichiro Shimomura +11 more
TL;DR: Novel biomarker candidates for atherosclerosis in Japanese patients with T2DM are identified using GC/MS-based non-targeted metabolomics using gas chromatography coupled with mass spectrometry highly optimized for multiple measurement of blood samples.