M
Masataka Takenaka
Researcher at Jikei University School of Medicine
Publications - 14
Citations - 237
Masataka Takenaka is an academic researcher from Jikei University School of Medicine. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 5, co-authored 9 publications receiving 168 citations.
Papers
More filters
Journal ArticleDOI
Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer.
Reika Iwakawa,Masataka Takenaka,Takashi Kohno,Yoko Shimada,Yasushi Totoki,Tatsuhiro Shibata,Koji Tsuta,Ryo Nishikawa,Masayuki Noguchi,Aiko Sato-Otsubo,Seishi Ogawa,Jun Yokota +11 more
TL;DR: It was indicated that amplification and fusion of several genes on chromosomes 1 and 8 occur simultaneously but not sequentially through chromothripsis in the development of SCLC, and amplification rather than fusion of genes plays an important role in its development.
Journal ArticleDOI
Somatic copy number alterations associated with Japanese or endometriosis in ovarian clear cell adenocarcinoma.
Aikou Okamoto,Jalid Sehouli,Nozomu Yanaihara,Yukihiro Hirata,Ioana Braicu,Byoung-Gie Kim,Satoshi Takakura,Misato Saito,Satoshi Yanagida,Masataka Takenaka,Noriko Yamaguchi,Asuka Morikawa,Hiroshi Tanabe,Kyosuke Yamada,Kosuke Yoshihara,Takayuki Enomoto,Hiroaki Itamochi,Junzo Kigawa,Noriomi Matsumura,Ikuo Konishi,Satoshi Aida,Yuko Aoki,Nobuya Ishii,Kazunori Ochiai,Tetsu Akiyama,Mitsuyoshi Urashima +25 more
TL;DR: There may be an association between CCC and ZNF217 amplification among Japanese patients as well as between endometriosis and EGFR gene amplifications, and no SCNAs were significantly associated with prognosis or thrombosis.
Journal ArticleDOI
Rethinking of Treatment Strategies and Clinical Management in Ovarian Clear Cell Carcinoma
TL;DR: Treatment strategies specific for OCCC based on its clinical and molecular characteristics are urgently needed because of its rarity and unique molecular characteristics.
Journal ArticleDOI
MicroRNA Gene Expression Signature Driven by miR-9 Overexpression in Ovarian Clear Cell Carcinoma.
Nozomu Yanaihara,Yukiko Noguchi,Misato Saito,Masataka Takenaka,Satoshi Takakura,Kyosuke Yamada,Aikou Okamoto +6 more
TL;DR: Global cancer-related miRNA expression analysis identified statistically unique profiles that could discriminate ovarian cancer histotypes that may affect pathogenesis by targeting E-cadherin and induce an epithelial–mesenchymal transition.
Journal ArticleDOI
Treatment Strategies for ARID1A-Deficient Ovarian Clear Cell Carcinoma
Kazuaki Takahashi,Kazuaki Takahashi,Kazuaki Takahashi,Masataka Takenaka,Aikou Okamoto,David D.L. Bowtell,David D.L. Bowtell,Takashi Kohno +7 more
TL;DR: In this paper, the authors proposed a molecularly targeted therapy that exploit the consequences of SWI/SNF deficiency may have clinical efficacy against ovarian clear cell carcinoma (OCCC), a major histological subtype of ovarian cancer.