M
Masayoshi Konishi
Researcher at Mie University
Publications - 25
Citations - 1001
Masayoshi Konishi is an academic researcher from Mie University. The author has contributed to research in topics: Hepatitis C virus & Immunogold labelling. The author has an hindex of 12, co-authored 25 publications receiving 981 citations. Previous affiliations of Masayoshi Konishi include University of Connecticut Health Center.
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Journal ArticleDOI
Hepatitis C virus particle detected by immunoelectron microscopic study
Masahiko Kaito,Shozo Watanabe,Kyoko Tsukiyama-Kohara,Kenjiro Yamaguchi,Yoshinao Kobayashi,Masayoshi Konishi,Masato Yokoi,Satoshi Ishida,Shiro Suzuki,Michinori Kohara +9 more
TL;DR: To clarify the morphology of hepatitis C virus (HCV), an indirect immunogold electron microscopic study was carried out on two plasma samples with high HCV RNA titres using polyclonal and monoclonal antibodies specific to the putative HCV envelope protein.
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Quantitation and typing of serum hepatitis C virus RNA in patients with chronic hepatitis C treated with interferon-β
M D Yoshinao Kobayashi,Shozo Watanabe,Masayoshi Konishi,Masato Yokoi,Ryuichi Kakehashi,Masahiko Kaito,Masahiro Kondo,Yuji Hayashi,Takahito Jomori,Shiro Suzuki +9 more
TL;DR: The results show that mixed infections with different hepatitis C virus subtypes appear to be more common than previously reported and that the pretreatment serum level of hepatitis Cirus RNA is a more important predictor of outcome of interferon therapy than is virus genotype.
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Inhibition of HBV replication by siRNA in a stable HBV-producing cell line.
TL;DR: In this paper, small interfering RNA molecules (siRNA) were applied against viral replication in a hepatitis B virus (HBV) model using HBV-specific siRNA against the polyadenylation (PA), precore (PreC), and surface (S) regions, respectively.
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Increased lipid peroxidation in patients with non-alcoholic fatty liver disease and chronic hepatitis C as measured by the plasma level of 8-isoprostane.
Masayoshi Konishi,Motoh Iwasa,Jun Araki,Yoshinao Kobayashi,Akira Katsuki,Yasuhiro Sumida,Naoki Nakagawa,Yuji Kojima,Shozo Watanabe,Yukihiko Adachi,Masahiko Kaito +10 more
TL;DR: Whether the degree of lipid peroxidation, as measured by the plasma level of 8‐isoprostane, influences the progression of chronic liver diseases and hepatocarcinogenesis is clarified.
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Restriction of dietary calories, fat and iron improves non-alcoholic fatty liver disease
Mika Yamamoto,Motoh Iwasa,Kazuko Iwata,Masahiko Kaito,Ryosuke Sugimoto,Naohito Urawa,Rumi Mifuji,Masayoshi Konishi,Yoshinao Kobayashi,Yukihiko Adachi +9 more
TL;DR: The aim of the present study was to evaluate the grade of hepatic iron accumulation and the therapeutic response to restriction of calories, fat and iron in patients with non‐alcoholic fatty liver disease (NAFLD).