M
Masayuki A. Fujino
Researcher at Juntendo University
Publications - 50
Citations - 4172
Masayuki A. Fujino is an academic researcher from Juntendo University. The author has contributed to research in topics: Gastric emptying & Elevated plus maze. The author has an hindex of 22, co-authored 49 publications receiving 4051 citations.
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Journal ArticleDOI
Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin.
Akihiro Asakawa,Akio Inui,Toshihiro Kaga,Hideki Yuzuriha,Toshiaki Nagata,Naohiko Ueno,Susumu Makino,Mineko Fujimiya,Akira Niijima,Masayuki A. Fujino,Masato Kasuga +10 more
TL;DR: Ghrelin, which is negatively regulated by leptin and IL-1 beta, is secreted by the stomach and increases arcuate NPY expression, which in turn acts through Y(1) receptors to increase food intake and decrease energy expenditure.
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Antagonism of ghrelin receptor reduces food intake and body weight gain in mice.
Akihiro Asakawa,Akio Inui,Toshihiro Kaga,Goro Katsuura,Mineko Fujimiya,Masayuki A. Fujino,Masato Kasuga +6 more
TL;DR: Gastric peptide ghrelin and GHS-R may be promising therapeutic targets not only for anorexia-cachexia but also for obesity and type 2 diabetes, which are becoming increasingly prevalent worldwide.
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Characterization of the effects of pancreatic polypeptide in the regulation of energy balance.
Akihiro Asakawa,Akio Inui,Hideki Yuzuriha,Naohiko Ueno,Goro Katsuura,Mineko Fujimiya,Masayuki A. Fujino,Akira Niijima,Michael M. Meguid,Michael M. Meguid,Masato Kasuga +10 more
TL;DR: Observations indicate that PP may influence food intake, energy metabolism, and the expression of hypothalamic peptides and gastric ghrelin.
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A role of ghrelin in neuroendocrine and behavioral responses to stress in mice
Akihiro Asakawa,Akio Inui,Toshihiro Kaga,Hideki Yuzuriha,Toshiaki Nagata,Mineko Fujimiya,Goro Katsuura,Susumu Makino,Masayuki A. Fujino,Masato Kasuga +9 more
TL;DR: The findings suggest that ghrelin may have a role in mediating neuroendocrine and behavioral responses to stressors and that the stomach could play an important role, not only in the regulation of appetite, but also in theregulation of anxiety.
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Accuracy of screening for gastric cancer using serum pepsinogen concentrations
TL;DR: Pepsinogen screening has many advantages, including its suitability for combination with other screening methods because it is simple and inexpensive, and the size of the lesion determines whether it is possible to detect cancer by serum pepsInogen screening.