M
Matej Lexa
Researcher at Masaryk University
Publications - 55
Citations - 956
Matej Lexa is an academic researcher from Masaryk University. The author has contributed to research in topics: Retrotransposon & Genome. The author has an hindex of 17, co-authored 54 publications receiving 719 citations. Previous affiliations of Matej Lexa include University of Padua & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Hammock: a hidden Markov model-based peptide clustering algorithm to identify protein-interaction consensus motifs in large datasets
TL;DR: The software tool presented in this article is able to rapidly identify multiple clusters of sequences carrying shared specificity motifs in massive datasets from various sources and generate multiple sequence alignments of identified clusters.
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Quadruplex-forming sequences occupy discrete regions inside plant LTR retrotransposons
Matej Lexa,Eduard Kejnovský,Pavlina Steflova,Helena Konvalinová,Michaela Vorlíčková,Boris Vyskot +5 more
TL;DR: It is found that PQSs were often located in LTRs, both upstream and downstream of promoters from which the whole retrotransposon is transcribed, indicating their role both at transcriptional and post-transcriptional levels.
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Guanine quadruplexes are formed by specific regions of human transposable elements
Matej Lexa,Pavlina Steflova,Tomáš Martínek,Michaela Vorlíčková,Michaela Vorlíčková,Boris Vyskot,Eduard Kejnovsky +6 more
TL;DR: It is found that PQSs are specifically localized in the 3’-UTR of LINE-1 elements, in LTRs of HERV elements and are strongly accumulated in specific regions of SVA elements.
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Bacterial but Not Fungal Gut Microbiota Alterations Are Associated With Common Variable Immunodeficiency (CVID) Phenotype.
Kristýna Fiedorová,Matěj Radvanský,Juraj Bosák,Hana Grombiříková,Eva Němcová,Pavlína Králíčková,Michaela Černochová,Iva Kotásková,Iva Kotásková,Matej Lexa,Jiří Litzman,David Šmajs,Tomáš Freiberger,Tomáš Freiberger +13 more
TL;DR: It is suggested that gut bacterial microbiota is altered in CVID patients and may be one of the missing environmental drivers contributing to some of the symptoms and disease severity.
Journal ArticleDOI
Growth and nitrogen relations in reciprocal grafts of wild-type and nitrate reductase-deficient mutants of pea (Pisum sativum L. var. Juneau)
Matej Lexa,John M. Cheeseman +1 more
TL;DR: It was found that changing the location of nitrate reduction did not change growth significantly and caused only subtle changes in N concentration, in spite of marked changes in growth associated with NO 3 - availability and useability.