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Matthew D. Bryant

Publications -  4
Citations -  561

Matthew D. Bryant is an academic researcher. The author has contributed to research in topics: Internal medicine & Genetically modified mouse. The author has an hindex of 2, co-authored 3 publications receiving 335 citations.

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A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures.

TL;DR: A model in mouse using a species-adapted virus recapitulates features of SARS-CoV-2 infection and age-related disease pathogenesis in humans, and provides a model system for rapid evaluation of medical countermeasures against coronavirus disease 2019 (COVID-19).
Posted ContentDOI

A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures

TL;DR: This mouse-adapted SARS-CoV-2 model demonstrates age-related disease pathogenesis and supports the clinical use of IFN lambda-1a treatment in human COVID-19 infections and shows that clinical candidate interferon (IFN) lambda- 1a can potently inhibit SARS's replication in primary human airway epithelial cells in vitro and both prophylactic and therapeutic administration diminished replication in mice.
Journal ArticleDOI

S1570 Diagnosis and Treatment of Celiac Disease Among Adults: A Qualitative Study Among Gastroenterologists

TL;DR: The authors conducted a qualitative study to assess the management of Celiac disease (CeD) among US GI, and found that compliance with a Gluten Free Diet (GFD) is the biggest challenge for many patients, which is of concern in about 40% of patients.