M
Matthew J. Allen
Researcher at University of Cambridge
Publications - 94
Citations - 2822
Matthew J. Allen is an academic researcher from University of Cambridge. The author has contributed to research in topics: Amorphous carbon & Bone metastasis. The author has an hindex of 25, co-authored 94 publications receiving 2595 citations. Previous affiliations of Matthew J. Allen include State University of New York System & Ohio State University.
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Journal ArticleDOI
Pro-inflammatory cytokines and the pathogenesis of Gaucher's disease : increased release of interleukin-6 and interleukin-10
TL;DR: Enhanced release of these cytokines from pathological macrophages provides a pathological link between Gaucher's disease and associated lympho-proliferative disorders.
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In vitro and in vivo investigations into the biocompatibility of diamond‐like carbon (DLC) coatings for orthopedic applications
TL;DR: Data indicate that DLC coatings are biocompatible in vitro and in vivo, and further investigations into their long-term biological and tribological performance are now warranted.
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Bone turnover mediates preferential localization of prostate cancer in the skeleton.
Abraham Schneider,Linda M. Kalikin,Ana C. Mattos,Evan T. Keller,Matthew J. Allen,Kenneth J. Pienta,Laurie K. McCauley +6 more
TL;DR: New evidence is provided that skeletal sites rich in marrow cellularity under active turnover offer a more congenial microenvironment to facilitate cancer localization in the skeleton to facilitate metastatic prostate cancer in bone.
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Preclinical evaluation of a poly (vinyl alcohol) hydrogel implant as a replacement for the nucleus pulposus.
Matthew J. Allen,Joanne E. Schoonmaker,Thomas W. Bauer,Philip F. Williams,Paul Higham,Hansen A. Yuan +5 more
TL;DR: Implantation of the PVA implant for periods of up to 24 months produced no evidence of local or systemic toxicity, and additional studies are now needed to determine the efficacy of the device in its intended application.
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The Effects Of Particulate Cobalt, Chromium And Cobalt-chromium Alloy On Human Osteoblast-like Cells In Vitro
TL;DR: In this article, the effects of particulate debris on the growth and metabolism of osteoblastic cells were investigated in vitro, showing that cobalt was toxic to both cell lines and inhibited the production of type-I collagen, osteocalcin and alkaline phosphatase.