M
Matthew J. Lovell
Researcher at Queen Mary University of London
Publications - 14
Citations - 485
Matthew J. Lovell is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Stem cell & Stem-cell therapy. The author has an hindex of 9, co-authored 14 publications receiving 464 citations. Previous affiliations of Matthew J. Lovell include Barts Health NHS Trust & National Institute for Health Research.
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Journal ArticleDOI
Mechanisms Underlying Erythrocyte and Endothelial Nitrite Reduction to Nitric Oxide in Hypoxia Role for Xanthine Oxidoreductase and Endothelial Nitric Oxide Synthase
Andrew J. Webb,Alexandra B. Milsom,Krishnaraj S. Rathod,Wai Lum Chu,Shehla Qureshi,Matthew J. Lovell,Florence Lecomte,David Perrett,Carmello Raimondo,Espeed Khoshbin,Zubair Ahmed,Rakesh Uppal,Nigel Benjamin,Adrian J. Hobbs,Amrita Ahluwalia +14 more
TL;DR: It is demonstrated that conversion of nitrite to NO by blood vessels and RBCs was enhanced in the presence of the Xor substrate xanthine and attenuated by the XOR inhibitor allopurinol in acidic and hypoxic conditions only.
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C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression
Ramona S. Scotland,Marc Cohen,Paul S. Foster,Matthew J. Lovell,Anthony Mathur,Amrita Ahluwalia,Adrian J. Hobbs +6 more
TL;DR: Analysis of human umbilical vein endothelial cells, leukocytes, and platelets revealed that CNP selectively attenuates expression of P-selectin, and suggest that endothelial CNP might maintain an anti-atherogenic influence on the blood vessel wall and represent a target for therapeutic intervention in inflammatory cardiovascular disorders.
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Cardiac stem cell therapy: progress from the bench to bedside
Matthew J. Lovell,Anthony Mathur +1 more
TL;DR: The progress to date in translating the exciting preclinical results of cardiac repair into man is summarized and the questions that this area of research has stimulated about the challenges of moving from bench to bedside are considered.
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The impact of acute kidney injury on midterm outcomes after coronary artery bypass graft surgery: A matched propensity score analysis
Sean Gallagher,Sean Gallagher,Sean Gallagher,Daniel A. Jones,Daniel A. Jones,Daniel A. Jones,Matthew J. Lovell,Matthew J. Lovell,Sevda Hassan,Andrew Wragg,Andrew Wragg,Akhil Kapur,Akhil Kapur,Akhil Kapur,Rakesh Uppal,Rakesh Uppal,Rakesh Uppal,Muhammad M. Yaqoob,Muhammad M. Yaqoob,Muhammad M. Yaqoob +19 more
TL;DR: The development of AKI after CABG is a serious event associated with worse midterm survival and cannot be explained simply by coexisting comorbidity and surgical complexity.
Journal ArticleDOI
The role of stem cells for treatment of cardiovascular disease.
Matthew J. Lovell,Anthony Mathur +1 more
TL;DR: Initial transplantation studies have demonstrated functional benefits and it is hoped further randomised clinical trials will concur with initial findings, and matters of concern are the role of cell fusion and the mechanisms by which transplanted cells improve cardiac function.