M
Matthew W Carroll
Researcher at University of Alberta
Publications - 54
Citations - 1440
Matthew W Carroll is an academic researcher from University of Alberta. The author has contributed to research in topics: Inflammatory bowel disease & Ulcerative colitis. The author has an hindex of 16, co-authored 48 publications receiving 888 citations. Previous affiliations of Matthew W Carroll include Canadian Association of Gastroenterology & Children's Medical Research Institute.
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Journal ArticleDOI
Trends in Epidemiology of Pediatric Inflammatory Bowel Disease in Canada: Distributed Network Analysis of Multiple Population-Based Provincial Health Administrative Databases
Eric I Benchimol,Charles N. Bernstein,Alain Bitton,Matthew W Carroll,Harminder Singh,Anthony R. Otley,Maria Vutcovici,Wael El-Matary,Geoffrey C. Nguyen,Anne M. Griffiths,David R. Mack,David R. Mack,Kevan Jacobson,Nassim Mojaverian,Divine Tanyingoh,Yunsong Cui,Zoann Nugent,Janie Coulombe,Laura E. Targownik,Jennifer Jones,Desmond Leddin,Sanjay K. Murthy,Gilaad G Kaplan +22 more
TL;DR: Canada has amongst the highest incidence of childhood-onset IBD in the world and prevalence significantly increased over time, with a rapid increase in incidence in the youngest group of children.
Journal ArticleDOI
Mucosal Barrier Depletion and Loss of Bacterial Diversity are Primary Abnormalities in Paediatric Ulcerative Colitis
Misagh Alipour,Deenaz Zaidi,Rosica Valcheva,Juan Jovel,Inés Martínez,Consolato Sergi,Jens Walter,Andrew Mason,Gane Ka-Shu Wong,Levinus A. Dieleman,Matthew W Carroll,Hien Q. Huynh,Eytan Wine +12 more
TL;DR: An underlying defect in the UC-afflicted intestinal tract even in the absence of inflammation is suggested, implicating barrier and microbial changes as primary abnormalities in UC that may play a causative role in disease development.
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Host immunoglobulin G selectively identifies pathobionts in pediatric inflammatory bowel diseases
H Armstrong,Misagh Alipour,Rosica Valcheva,Michael Bording-Jorgensen,Juan Jovel,Deenaz Zaidi,Prachi E. Shah,Yuefei Lou,Cory Ebeling,Andrew Mason,Dawson Lafleur,J Jerasi,Gane Ka-Shu Wong,Karen Madsen,Matthew W Carroll,Hien Q. Huynh,Levinus A. Dieleman,Eytan Wine +17 more
TL;DR: Using IgG as a marker of pathobionts in larger patient cohorts to identify microbes and elucidate their role in IBD pathogenesis will potentially underpin new strategies to facilitate development of novel, targeted diagnostic, and therapeutic approaches.
Journal ArticleDOI
The Impact of Inflammatory Bowel Disease in Canada 2018: Children and Adolescents with IBD
Matthew W Carroll,M Ellen Kuenzig,David R. Mack,Anthony R. Otley,Anne M. Griffiths,Gilaad G. Kaplan,Charles N. Bernstein,Alain Bitton,Sanjay K. Murthy,Geoffrey C. Nguyen,Kate Lee,Jane Cooke-Lauder,Eric I Benchimol +12 more
TL;DR: The treatment of children with IBD presents important challenges including therapeutic choices, risk of adverse events to medications, psychosocial impact on the child and family, increased cost of health care and the implications of the transition from pediatric to adult care.
Journal ArticleDOI
Rural and Urban Residence During Early Life is Associated with Risk of Inflammatory Bowel Disease: A Population-Based Inception and Birth Cohort Study
Eric I Benchimol,Gilaad G. Kaplan,Anthony R. Otley,Geoffrey C. Nguyen,Fox E. Underwood,Astrid Guttmann,Jennifer Jones,Beth K. Potter,Christina Catley,Zoann Nugent,Yunsong Cui,Divine Tanyingoh,Nassim Mojaverian,Alain Bitton,Matthew W Carroll,Jennifer deBruyn,Trevor J.B. Dummer,Wael El-Matary,Anne M. Griffiths,Kevan Jacobson,M Ellen Kuenzig,Desmond Leddin,Lisa M. Lix,David R. Mack,David R. Mack,Sanjay K. Murthy,Juan Nicolás Peña Sánchez,Harminder Singh,Laura E. Targownik,Maria Vutcovici,Charles N. Bernstein +30 more
TL;DR: People living in rural households had lower risk of developing IBD, and in children exposed to the rural environment early in life, this association is strongest in young children and adolescents.