M
Matthew West
Researcher at University of Colorado Boulder
Publications - 24
Citations - 3164
Matthew West is an academic researcher from University of Colorado Boulder. The author has contributed to research in topics: Endosome & ESCRT. The author has an hindex of 13, co-authored 24 publications receiving 2727 citations. Previous affiliations of Matthew West include University of Colorado Denver.
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Journal ArticleDOI
ER Tubules Mark Sites of Mitochondrial Division
Jonathan R. Friedman,Laura L. Lackner,Matthew West,Jared R. DiBenedetto,Jodi Nunnari,Gia K. Voeltz +5 more
TL;DR: It was found that mitochondrial division occurred at positions where ER tubules contacted mitochondria and mediated constriction before Drp1 recruitment, suggesting that ERtubules may play an active role in defining the position of mitochondrial division sites.
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A 3D analysis of yeast ER structure reveals how ER domains are organized by membrane curvature
TL;DR: Electron tomography of continuous ER domains during budding shows that reticulons and Yop1 stabilize rather than generate membrane curvature in this organelle.
Journal ArticleDOI
ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast
Andrew Murley,Laura L. Lackner,Christof Osman,Matthew West,Gia K. Voeltz,Peter Walter,Jodi Nunnari +6 more
TL;DR: It is shown that mitochondrial division is spatially linked to nucleoids and that a majority of these nucleoids segregate prior to division, resulting in their distribution into newly generated tips in the mitochondrial network.
Journal ArticleDOI
Endoplasmic reticulum–endosome contact increases as endosomes traffic and mature
TL;DR: Endosomes do not traffic autonomously but instead associate with the ER membrane, which suggests that the ER might play a role in endosomal maturation.
Journal ArticleDOI
Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes.
TL;DR: The uncoupling of MVB cargo sorting and lumenal vesicle formation suggests that the Vps4-mediated dissociation of ESCRT-III is an essential step in the sorting of cargo proteins into MVB vesicles but is not a prerequisite for the budding of vesicular budding into the endosome lumen.