Showing papers by "Matthias Breuning published in 2006"
TL;DR: In this article, a homopipecolic acid methyl ester was prepared on a multigram scale from 3,4-dihydro-2H-pyran in five steps and 36% overall yield.
Abstract: (R)-Homopipecolic acid methyl ester has been prepared on a multigram scale from 3,4-dihydro-2H-pyran in five steps and 36% overall yield. The stereochemistry was introduced via an asymmetric Michael addition and a fractional crystallization.
8 citations