M
Matthias Ludwig
Researcher at Ludwig Maximilian University of Munich
Publications - 15
Citations - 277
Matthias Ludwig is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Enantioselective synthesis & Formal specification. The author has an hindex of 9, co-authored 15 publications receiving 274 citations.
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Journal ArticleDOI
Web-based modelling of energy, water and matter fluxes to support decision making in mesoscale catchments - the integrative perspective of GLOWA-Danube
Ralf Ludwig,Wolfram Mauser,S. Niemeyer,A. Colgan,R. Stolz,Heidi Escher-Vetter,Michael Kuhn,Markus Reichstein,John Tenhunen,Andreas Kraus,Matthias Ludwig,M. Barth,Rolf Hennicker +12 more
TL;DR: The GLOWA-Danube project as mentioned in this paper developed an integrated decision support system, called DANUBIA, to investigate the sustainability of future water use in the Upper Danube watershed.
Journal ArticleDOI
Affinity of 1-aryl-1,2,3,4-tetrahydroisoquinoline derivatives to the ion channel binding site of the NMDA receptor complex.
TL;DR: A convenient and efficient synthetic approach to racemic 1-aryl-1,2,3,4-tetrahydroisoquinoline derivatives is described and shows a remarkable enantioselectivity of binding by being almost 90 times more potent than the corresponding (R)-enantiomer (R-4 e x HCl.
Journal ArticleDOI
Danubia: an integrative simulation system for global change research in the upper danube basin
TL;DR: The concepts and design principles of the integrative simulation system DANUBIA, which supports the analysis of water-related global change scenarios in the Upper Danube Basin, are described and an overview of the architecture of the DAN UBIA implementation that has been realized in Java is provided.
Journal ArticleDOI
Asymmetric Synthesis and Enantioselectivity of Binding of 1-Aryl-1,2,3,4-tetrahydroisoquinolines at the PCP Site of the NMDA Receptor Complex
TL;DR: The enantiomerically pure 11c–g and 12c-g (ee > 99 %), 1-aryl-tetrahydroisoquinolines, were evaluated for their affinity to the PCP [1-(1-phenylcyclohexyl)piperidine] binding site of the NMDA (N-methyl D-aspartate) receptor and in each case the enantiomers 11 exhibited a higher affinity than those of 12.
A Generic Framework for Multi-Disciplinary Environmental Modelling
TL;DR: A generic framework for computer-based environmental modelling which supports the coupling of simulation models from various sciences to perform integrative simula- tions and is applicable to any kind of model which simulates spatially distributed environmental processes with an arbitrary, but discrete, time scale.