M
Maude Tremblay-Létourneau
Researcher at Université de Sherbrooke
Publications - 7
Citations - 182
Maude Tremblay-Létourneau is an academic researcher from Université de Sherbrooke. The author has contributed to research in topics: RNA & RNA splicing. The author has an hindex of 6, co-authored 7 publications receiving 129 citations.
Papers
More filters
Journal ArticleDOI
Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions.
Simon Boudreault,Camille Martenon-Brodeur,Marie Caron,Jean-Michel Garant,Marie-Pier Tremblay,Victoria E. S. Armero,Mathieu Durand,Elvy Lapointe,Philippe Thibault,Maude Tremblay-Létourneau,Jean-Pierre Perreault,Michelle S. Scott,Guy Lemay,Martin Bisaillon +13 more
TL;DR: This study identifies 240 modified alternative splicing events upon infection which belong to transcripts frequently involved in the regulation of gene expression and RNA metabolism and confirms modifications to transcript-specific peptides resulting from AS in virus- infected cells.
Journal ArticleDOI
Global profiling of alternative RNA splicing events provides insights into molecular differences between various types of hepatocellular carcinoma
Marie-Pier Tremblay,Victoria E. S. Armero,Andréa Allaire,Simon Boudreault,Camille Martenon-Brodeur,Mathieu Durand,Elvy Lapointe,Philippe Thibault,Maude Tremblay-Létourneau,Jean-Pierre Perreault,Michelle S. Scott,Martin Bisaillon +11 more
TL;DR: This study provides the first comprehensive portrait of global changes in the RNA splicing signatures that occur in hepatocellular carcinoma using high-throughput RNA sequencing data.
Journal ArticleDOI
2'-O-methylation of the mRNA cap protects RNAs from decapping and degradation by DXO.
Frédéric Picard-Jean,Carolin Brand,Maude Tremblay-Létourneau,Andréa Allaire,Maxime C. Beaudoin,Simon Boudreault,Cyntia Duval,Julien Rainville-Sirois,Francis Robert,Jerry Pelletier,Brian J. Geiss,Martin Bisaillon +11 more
TL;DR: It is demonstrated that DXO possesses both decapping and exoribonuclease activities toward incompletely capped RNAs, only sparing RNAs with a 2’-O-methylated cap structure.
Journal ArticleDOI
Transcriptome-wide analysis of alternative RNA splicing events in Epstein-Barr virus-associated gastric carcinomas.
Victoria E. S. Armero,Marie-Pier Tremblay,Andréa Allaire,Simon Boudreault,Camille Martenon-Brodeur,Cyntia Duval,Mathieu Durand,Elvy Lapointe,Philippe Thibault,Maude Tremblay-Létourneau,Jean-Pierre Perreault,Michelle S. Scott,Martin Bisaillon +12 more
TL;DR: Modifications to the global RNA splicing landscape of cellular genes were investigated in the context of Epstein-Barr virus-associated gastric cancer and it is shown that the expression of Epstein–Barr nuclear antigen 1 (EBNA1) leads to modifications in the AS profile of cellular molecules and that the EBNA1 protein interacts with cellular splicing factors.