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Mauricio Tohen

Researcher at University of New Mexico

Publications -  476
Citations -  34199

Mauricio Tohen is an academic researcher from University of New Mexico. The author has contributed to research in topics: Bipolar disorder & Olanzapine. The author has an hindex of 95, co-authored 464 publications receiving 32214 citations. Previous affiliations of Mauricio Tohen include University of Minnesota & University of Alabama at Birmingham.

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Telephone versus in-person clinical and health status assessment interviews in patients with bipolar disorder.

TL;DR: Phone interviews are feasible and reliable for collecting data on psychiatric and other health‐related outcomes in bipolar disorder patients and indicate good to excellent agreement on measures of mania and depression symptoms.
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DSM-5 mixed specifier for manic episodes: evaluating the effect of depressive features on severity and treatment outcome using asenapine clinical trial data.

TL;DR: These analyses support the validity of proposed DSM-5 criteria and confirm that depressive features are frequent in bipolar patients with manic episodes.
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Antipsychotic agents in the treatment of bipolar mania

TL;DR: Evidence exists on the efficacy of both typical and atypical antipsychotics on the treatment of acute mania such that they are now clearly first-line along with lithium.
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Effects of olanzapine alone and olanzapine/fluoxetine combination on health-related quality of life in patients with bipolar depression: secondary analyses of a double-blind, placebo-controlled, randomized clinical trial.

TL;DR: Based on these analyses, patients with bipolar depression receiving olanzapine or OFC for 8 weeks had greater improvement in HRQOL than those receiving placebo, and correlation results support the construct validity of the QLDS.
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Olanzapine/fluoxetine combination for the treatment of mixed depression in bipolar I disorder: a post hoc analysis.

TL;DR: It was found that no baseline manic/hypomanic symptom of mixed depression predicted treatment response, and a higher number of baseline concurrent manic/ Hypomanic symptoms predicted a lower response rate in the olanzapine and placebo arms, but not in the OFC arm.