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Mark A. Frye

Researcher at Mayo Clinic

Publications -  476
Citations -  24585

Mark A. Frye is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Bipolar disorder & Mania. The author has an hindex of 67, co-authored 417 publications receiving 20910 citations. Previous affiliations of Mark A. Frye include West Los Angeles College & Veterans Health Administration.

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Genome-wide association study identifies 30 loci associated with bipolar disorder

Eli A. Stahl, +342 more
- 01 May 2019 - 
TL;DR: Genome-wide analysis identifies 30 loci associated with bipolar disorder, allowing for comparisons of shared genes and pathways with other psychiatric disorders, including schizophrenia and depression.
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Epidemiology of vertebral fractures in women

TL;DR: Vertebral fracture prevalence was assessed in an age-stratified random sample of Rochester, Minnesota women aged 50 years and over, finding that vertebral fractures were common and increased with age.
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Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Phil Lee, +606 more
- 12 Dec 2019 - 
TL;DR: Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes.
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Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder

TL;DR: Comorbid lifetime and current axis I disorders in 288 patients with bipolar disorder and the relationships of these comorbid disorders to selected demographic and historical illness variables showed associations with earlier age at onset of affective symptoms and syndromal bipolar disorder.
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Screening for bipolar disorder in the community

TL;DR: The positive MDQ screen rate of 3.7% suggests that nearly 4% of American adults may suffer from bipolar I and II disorders, and young adults and individuals with lower income are at greater risk for this largely underdiagnosed disorder.