M
Mauro Provinciali
Researcher at Advanced Technology Center
Publications - 214
Citations - 5342
Mauro Provinciali is an academic researcher from Advanced Technology Center. The author has contributed to research in topics: Cytotoxic T cell & Population. The author has an hindex of 38, co-authored 200 publications receiving 4690 citations. Previous affiliations of Mauro Provinciali include Marche Polytechnic University & University of Perugia.
Papers
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Journal ArticleDOI
Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice.
Vladimir N. Anisimov,L. M. Berstein,Peter A. Egormin,Tatiana S. Piskunova,Irina G. Popovich,Mark A. Zabezhinski,Irina G. Kovalenko,Tatiana E. Poroshina,Anna V. Semenchenko,Mauro Provinciali,Francesca Re,Claudio Franceschi +11 more
TL;DR: The metformin-treatment significantly decreased the incidence and size of mammary adenocarcinomas in mice and increased the mean latency of the tumors, suggesting that the life-prolonging effects of calorie restriction are due to decreasing IGF-1 levels.
Journal ArticleDOI
Moving against frailty: does physical activity matter?
Francesco Landi,Angela Marie Abbatecola,Mauro Provinciali,Andrea Corsonello,Silvia Bustacchini,Luca Manigrasso,Antonio Cherubini,Roberto Bernabei,Fabrizia Lattanzio +8 more
TL;DR: This review will address the role of physical activity on the most relevant components of frailty syndrome, with specific reference to sarcopenia, as a condition which frequently overlaps with frailty.
Journal ArticleDOI
Effect of resveratrol on the development of spontaneous mammary tumors in HER‐2/neu transgenic mice
Mauro Provinciali,Francesca Re,Alessia Donnini,Fiorenza Orlando,Beatrice Bartozzi,Grazia Di Stasio,Arianna Smorlesi +6 more
TL;DR: It is demonstrated that Res supplementation delays the development and reduces the metastasizing capacity of spontaneous mammary tumors in HER‐2/neu transgenic mice.
Journal ArticleDOI
Pituitary-thyroid axis and immune system: a reciprocal neuroendocrine-immune interaction.
TL;DR: The present paper aims at summarizing the data available on the existence of thyroid-immune interactions, and at analyzing the possible integration between pituitary-thyroid hormones and immune factors in favoring the development and maintenance of both thymic and peripheral immune efficiency.
Journal ArticleDOI
DNA vaccination with full-length or truncated neu induces protective immunity against the development of spontaneous mammary tumors in HER-2/neu transgenic mice.
Augusto Amici,Arianna Smorlesi,Giuseppe Noce,Giorgio Santoni,P. Cappelletti,Lorena Capparuccia,Roberto Coppari,Roberta Lucciarini,Cristina Petrelli,Mauro Provinciali +9 more
TL;DR: The data demonstrate the effectiveness of DNA vaccination using truncated Neu plasmids in inducing antitumor protection in a spontaneous mammary tumor model.