M
Megha Saraswat
Researcher at National Institute of Nutrition, Hyderabad
Publications - 8
Citations - 909
Megha Saraswat is an academic researcher from National Institute of Nutrition, Hyderabad. The author has contributed to research in topics: Lens protein & Polyol pathway. The author has an hindex of 7, co-authored 8 publications receiving 867 citations.
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Journal ArticleDOI
Curcumin and turmeric delay streptozotocin-induced diabetic cataract in rats.
P. Suryanarayana,Megha Saraswat,Tiruvalluru Mrudula,T. Prasanna Krishna,Kamala Krishnaswamy,G. Bhanuprakash Reddy +5 more
TL;DR: The present studies suggest that curcumin and turmeric treatment appear to have countered the hyperglycemia-induced oxidative stress, because there was a reversal of changes with respect to lipid peroxidation, reduced glutathione, protein carbonyl content and activities of antioxidant enzymes in a significant manner.
Journal Article
Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract.
TL;DR: Results indicate that tannoids of E. officinalis are potent inhibitors of AR and suggest that exploring the therapeutic value of natural ingredients that people can incorporate into everyday life may be an effective approach in the management of diabetic complications.
Journal Article
Emblica officinalis and its enriched tannoids delay streptozotocin-induced diabetic cataract in rats.
TL;DR: It is pointed out that Emblica and its tannoids might counter the polyol pathway-induced oxidative stress as there was a reversal of changes with respect to lipid peroxidation, protein carbonyl content, and activities of antioxidant enzymes.
Journal ArticleDOI
Dietary sources of aldose reductase inhibitors: prospects for alleviating diabetic complications
TL;DR: The scope of adapting life-style modifications in the form of inclusion of certain common sources in the diet for the management of diabetic complications is indicated, as well as the importance of prevention of intracellular sorbitol accumulation.
Journal Article
Antiglycating potential of Zingiber officinalis and delay of diabetic cataract in rats.
Megha Saraswat,P. Suryanarayana,P. Y. Reddy,Madhoosudan A. Patil,Nagalla Balakrishna,Geereddy Bhanuprakash Reddy +5 more
TL;DR: The results indicated that ginger was effective against the development of diabetic cataract in rats mainly through its antiglycating potential and to a lesser extent by inhibition of the polyol pathway.