J. Mark Petrash

TL;DR: This paper presents a new probabilistic method for estimating the response of the immune system to EMTs to laser-spot assisted, 3D image analysis of EMMARM, which shows clear patterns in the response to laser beams.

TL;DR: A role for a relative or absolute increase in NO production in the pathogenesis of early diabetic vascular dysfunction is suggested and the possibility that inhibition of diabetic vascular functional changes by aminoguanidine may reflect inhibition of NO synthase activity rather than, or in addition to, prevention of AGE formation is raised.

TL;DR: It is demonstrated that mice unable to metabolize fructose are protected from an increase in energy intake and body weight, visceral obesity, fatty liver, elevated insulin levels and hyperleptinemia after exposure to 10% glucose for 14 weeks and concluded that endogenous fructose generation and metabolism in the liver represents an important mechanism whereby glucose promotes the development of metabolic syndrome.

TL;DR: In this paper, the chaperone activity and biophysical properties of recombinant human alphaA- and alphaB-crystallins were studied by light scattering and spectroscopic methods.

TL;DR: Results indicate that tannoids of E. officinalis are potent inhibitors of AR and suggest that exploring the therapeutic value of natural ingredients that people can incorporate into everyday life may be an effective approach in the management of diabetic complications.