Mehreen Ghufran

TL;DR: The results of the phytochemical analysis of these medicinal plants showed that the terpenoids, phlobatannins, reducing sugar, flavonoids and alkaloids were found to be present in afore mentioned medicinal plants.

TL;DR: In silico studies were performed to rationalize the binding mode of compounds (ligands) with the active site of α-amylase enzyme, and cytotoxicity of the compounds were checked on NIH-3T3 mouse fibroblast cell line and found to be non-toxic.

TL;DR: A structure activity relationship has been established on the basis of electronic effects and position of different substituents present on phenyl ring and in order to rationalize the binding interactions of most active analogues with the active site of α-glucosidase enzyme, molecular docking study was conducted.

TL;DR: The newly identified hybrid class of coumarin and thiazole substituted coumarins may serve as potential lead candidates for the management of diabetes mellitus.

TL;DR: Dihydropyrimidones 1-37 were synthesized via a 'one-pot' three component reaction according to well-known Biginelli reaction by utilizing Cu(NO3)2·3H2O as catalyst, and screened for in vitro β-glucuronidase inhibitory activity.