M
Mei Shan Ong
Researcher at National University of Singapore
Publications - 8
Citations - 562
Mei Shan Ong is an academic researcher from National University of Singapore. The author has contributed to research in topics: Cytoskeleton & Microtubule. The author has an hindex of 6, co-authored 7 publications receiving 341 citations.
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Journal ArticleDOI
Dual role of autophagy in hallmarks of cancer.
Shikha Satendra Singh,Somya Vats,Amelia Yi-Qian Chia,Tuan Zea Tan,Shuo Deng,Mei Shan Ong,Frank Arfuso,Celestial T. Yap,Boon Cher Goh,Gautam Sethi,Gautam Sethi,Ruby Yun-Ju Huang,Ruby Yun-Ju Huang,Han-Ming Shen,Ravi Manjithaya,Alan Prem Kumar +15 more
TL;DR: This review will provide a novel insight into the mutational landscapes of autophagy-related genes in several human cancers, using genetic information collected from an array of cancers.
Journal ArticleDOI
Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for Cancer Metastasis.
Arpita Datta,Shuo Deng,Vennila Gopal,Kenneth Chun-Hong Yap,Clarissa Esmeralda Halim,Mun Leng Lye,Mei Shan Ong,Tuan Zea Tan,Gautam Sethi,Shing Chuan Hooi,Alan Prem Kumar,Celestial T. Yap,Celestial T. Yap +12 more
TL;DR: In this article, a review summarizes the physiological functions of the cytoskeleton, its role in the epithelial to mesenchymal transition (EMT) process, and its effect on multidrug resistant (MDR) cancer cells.
Journal ArticleDOI
Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic Perspective
Mei Shan Ong,Shuo Deng,Clarissa Esmeralda Halim,Wanpei Cai,Tuan Zea Tan,Ruby Yun-Ju Huang,Ruby Yun-Ju Huang,Ruby Yun-Ju Huang,Gautam Sethi,Gautam Sethi,Shing Chuan Hooi,Alan Prem Kumar,Celestial T. Yap,Celestial T. Yap +13 more
TL;DR: The cytoskeletal responses to important intracellular stresses (such as mitochondrial, endoplasmic reticulum and oxidative stresses) are discussed, and the consequences of these responses are delineated, including effects on oncogenic signalling.
Journal ArticleDOI
Breast Cancer: Exploring the Facts and Holistic Needs During and Beyond Treatment
TL;DR: An overview of the holistic needs of breast cancer patients at each stage of their cancer journey, addressing their complex physical, psychological, and social needs is provided.
Journal ArticleDOI
Involvement of STAT5 in Oncogenesis.
TL;DR: Since STAT5 contributes to tumour aggressiveness and cancer progression, inhibiting STAT5 constitutive activation in cancers that rely on its signalling makes for a promising targeted treatment option.