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Wanpei Cai
Researcher at National University of Singapore
Publications - 10
Citations - 679
Wanpei Cai is an academic researcher from National University of Singapore. The author has contributed to research in topics: Metastasis & Cancer. The author has an hindex of 8, co-authored 10 publications receiving 499 citations.
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Journal ArticleDOI
Triple negative breast cancer in Asia: An insider's view.
Chao Wang,Shreya Kar,Xianning Lai,Wanpei Cai,Frank Arfuso,Gautam Sethi,Peter E. Lobie,Boon Cher Goh,Lina H. K. Lim,Mikael Hartman,Ching Wan Chan,Soo Chin Lee,Sing H. Tan,Alan Prem Kumar +13 more
TL;DR: This review encapsulates the studies conducted on TNBC patients in Asian population and elucidates the similarities and differences between these two regions to facilitate the development of better treatment strategies to combat TNBC.
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Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?
Shikha Satendra Singh,Wei Ney Yap,Frank Arfuso,Shreya Kar,Chao Wang,Wanpei Cai,Arunasalam Dharmarajan,Gautam Sethi,Alan Prem Kumar +8 more
TL;DR: The common dysregulation of PI3K/Akt/mTOR pathway in GC and the various types of single or dual pathway inhibitors under development that might have a superior role in GC treatment are reviewed and the recent developments in identification of predictive biomarkers are summarized.
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Secreted frizzled related proteins: Implications in cancers.
Rohit Surana,Sakshi Sikka,Wanpei Cai,Eun Myoung Shin,Sudha Warrier,Hong Jie Gabriel Tan,Frank Arfuso,Simon A. Fox,Arun Dharmarajan,Alan Prem Kumar +9 more
TL;DR: This review comprehensively covers all the available information on the role of SFRP molecules in various human cancers and identifies potential tools in combating Wnt-driven tumorigenesis.
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microRNAs in breast cancer: regulatory roles governing the hallmarks of cancer
Jen Nee Goh,Ser Y. Loo,Ser Y. Loo,Arpita Datta,Kodappully Sivaraman Siveen,Wei Ney Yap,Wanpei Cai,Eun Myoung Shin,Chao Wang,Ji E. Kim,Maurice Chan,Arun Dharmarajan,Ann S.-G. Lee,Peter E. Lobie,Celestial T. Yap,Alan Prem Kumar +15 more
TL;DR: This review provides a comprehensive overview of microRNAs with established functional relevance in breast cancer, their established target genes and resulting cellular phenotype, and the role and application of circulating miRNAs in breast cancers.
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Wanted DEAD/H or Alive: Helicases Winding Up in Cancers.
Wanpei Cai,Zhi Xiong Chen,Grishma Rane,Shikha Satendra Singh,Zhang'e Choo,Chao Wang,Yi Yuan,Tuan Zea Tan,Frank Arfuso,Celestial T. Yap,Lorinc S Pongor,Henry Yang,Martin B. Lee,Boon Cher Goh,Gautam Sethi,Touati Benoukraf,Vinay Tergaonkar,Alan Prem Kumar +17 more
TL;DR: Next-generation sequencing data obtained from public portals and reviewing existing literature are analyzed to provide new insights on the potential of DEAD/H-box helicases to act as pharmacological drug targets in cancers and the potential small molecule inhibitors of helicases and their therapeutic value are discussed.