S
Shikha Satendra Singh
Researcher at National University of Singapore
Publications - 13
Citations - 707
Shikha Satendra Singh is an academic researcher from National University of Singapore. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 5, co-authored 9 publications receiving 492 citations.
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Journal ArticleDOI
Dual role of autophagy in hallmarks of cancer.
Shikha Satendra Singh,Somya Vats,Amelia Yi-Qian Chia,Tuan Zea Tan,Shuo Deng,Mei Shan Ong,Frank Arfuso,Celestial T. Yap,Boon Cher Goh,Gautam Sethi,Gautam Sethi,Ruby Yun-Ju Huang,Ruby Yun-Ju Huang,Han-Ming Shen,Ravi Manjithaya,Alan Prem Kumar +15 more
TL;DR: This review will provide a novel insight into the mutational landscapes of autophagy-related genes in several human cancers, using genetic information collected from an array of cancers.
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Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?
Shikha Satendra Singh,Wei Ney Yap,Frank Arfuso,Shreya Kar,Chao Wang,Wanpei Cai,Arunasalam Dharmarajan,Gautam Sethi,Alan Prem Kumar +8 more
TL;DR: The common dysregulation of PI3K/Akt/mTOR pathway in GC and the various types of single or dual pathway inhibitors under development that might have a superior role in GC treatment are reviewed and the recent developments in identification of predictive biomarkers are summarized.
Journal ArticleDOI
Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells
Kodappully Sivaraman Siveen,An H. Nguyen,Jong Hyun Lee,Feng Li,Shikha Satendra Singh,Alan Prem Kumar,G Low,Sujeet Jha,Vinay Tergaonkar,Kwang Seok Ahn,Gautam Sethi +10 more
TL;DR: Lupeol exhibited its potential anticancer effects in HCC through the downregulation of STAT3-induced pro-survival signalling cascade through the involvement of a phosphatase.
Journal ArticleDOI
Generalized anxiety disorder in urban China: Prevalence, awareness, and disease burden
TL;DR: GAD may be substantially under-diagnosed in urban China and more healthcare resources should be invested to alleviate the burden of GAD.
Journal ArticleDOI
Cell-free Epstein-Barr virus-DNA in patients with nasopharyngeal carcinoma: Plasma versus urine.
Manju Sengar,Siddhesh Chorghe,Kamini Jadhav,Shikha Satendra Singh,Sarbani Ghosh Laskar,Prathamesh S. Pai,Jai Prakash Aggarwal,Anil K. D'Cruz,Pankaj Chaturvedi,Mandar S. Deshpande,Devendra Chaukar,Ashwini Budrukkar,Tejpal Gupta,Vedang Murthy,Shubhada Kane,Meenakshi Thakur,Venkatesh Rangarajan,Sadhana Kannan,Tanuja Shet,Jyoti Kode +19 more
TL;DR: The purpose of this study was to explore urinary Epstein–Barr virus (EBV)‐DNA as a potential biomarker in patients with nasopharyngeal carcinoma (NPC).