M
Melanie Kettering
Researcher at Schiller International University
Publications - 10
Citations - 288
Melanie Kettering is an academic researcher from Schiller International University. The author has contributed to research in topics: Magnetic nanoparticles & Particle. The author has an hindex of 6, co-authored 10 publications receiving 261 citations.
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Magnetic multicore nanoparticles for hyperthermia—influence of particle immobilization in tumour tissue on magnetic properties
TL;DR: The magnetic ex vivo characterization of the removed tumour tissue gave clear evidence for the immobilization of the particles in the tumours because the particlesIn the tumour showed the same magnetic behaviour as immobilized particles.
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Characterization of iron oxide nanoparticles adsorbed with cisplatin for biomedical applications
Melanie Kettering,Heike Zorn,Sibylle Bremer-Streck,Hartmut Oehring,Matthias Zeisberger,Christian Bergemann,Rudolf Hergt,Karl-Jürgen Halbhuber,Werner A. Kaiser,Ingrid Hilger +9 more
TL;DR: Cis-MNPs exhibit advantageous features for a facilitated desorption of cisplatin in biological media and the heating potential is adequate for hyperthermic treatments.
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The exposure of cancer cells to hyperthermia, iron oxide nanoparticles, and mitomycin C influences membrane multidrug resistance protein expression levels
TL;DR: The combination of different effectors like hyperthermia, iron oxide nanoparticles, and chemotherapeutics influences expression of MRP 1 and 3 in an adenocarcinoma cell line, thereby improving the therapeutic outcome in oncology.
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Magnetic thermoablation stimuli alter BCL2 and FGF-R1 but not HSP70 expression profiles in BT474 breast tumors.
TL;DR: Taken together, thermoablative heating induced via magnetic methods can reduce the expression of tumor-related proteins and locally inactivate tumor tissue, leading to a prospectively reduced tumorigenicity of cancerous tissues.
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Means to increase the therapeutic efficiency of magnetic heating of tumors.
Melanie Kettering,Ina Grau,Nadine Pömpner,Marcus Stapf,Mieczyslaw Gajda,Ulf Teichgräber,Ingrid Hilger +6 more
TL;DR: This study summarized the present knowledge on how to improve the therapeutic efficiency of magnetic hyperthermia using magnetic nanoparticles (MNPs), with particular consideration of the intratumoral infiltration of the magnetic material.