M
Melanie Meersch
Researcher at University of Münster
Publications - 74
Citations - 4337
Melanie Meersch is an academic researcher from University of Münster. The author has contributed to research in topics: Acute kidney injury & Medicine. The author has an hindex of 17, co-authored 52 publications receiving 2922 citations.
Papers
More filters
Journal ArticleDOI
Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury: The ELAIN Randomized Clinical Trial
Alexander Zarbock,John A. Kellum,Christoph Schmidt,Hugo Van Aken,Carola Wempe,Hermann Pavenstädt,Andreea Boanta,Joachim Gerß,Melanie Meersch +8 more
TL;DR: To determine whether early initiation of RRT in patients who are critically ill with AKI reduces 90-day all-cause mortality, a single-center randomized clinical trial of 231 critically ill patients with KDIGO stage 2 found that more patients in the early group recovered renal function by day 90.
Journal ArticleDOI
Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial
Melanie Meersch,Christoph Schmidt,Andreas Hoffmeier,Hugo Van Aken,Carola Wempe,Joachim Gerss,Alexander Zarbock +6 more
TL;DR: In this article, the efficacy of an implementation of the Kidney Disease Improving Global Outcomes (KDIGO) guidelines to prevent cardiac surgery-associated acute kidney injury (AKI) in high risk patients defined by renal biomarkers was evaluated.
Journal ArticleDOI
Erratum to: Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial.
Melanie Meersch,Christoph Schmidt,Andreas Hoffmeier,Hugo Van Aken,Carola Wempe,Joachim Gerss,Alexander Zarbock +6 more
TL;DR: An implementation of the KDIGO guidelines compared with standard care reduced the frequency and severity of AKI after cardiac surgery in high risk patients.
Journal ArticleDOI
Urinary TIMP-2 and IGFBP7 as Early Biomarkers of Acute Kidney Injury and Renal Recovery following Cardiac Surgery
Melanie Meersch,Christoph Schmidt,Hugo Van Aken,Sven Martens,Jan Rossaint,Kai Singbartl,Dennis Görlich,John A. Kellum,Alexander Zarbock +8 more
TL;DR: Urinary [TIMP-2]*[IGFBP7] serves as a sensitive and specific biomarker to predict AKI early after cardiac surgery and to predict renal recovery in patients who developed AKI.
Journal ArticleDOI
Effect of remote ischemic preconditioning on kidney injury among high-risk patients undergoing cardiac surgery: a randomized clinical trial.
Alexander Zarbock,Christoph Schmidt,Hugo Van Aken,Carola Wempe,Sven Martens,Peter K. Zahn,Britta Wolf,Ulrich Goebel,Christian I. Schwer,Peter Rosenberger,Helene A. Haeberle,Dennis Görlich,John A. Kellum,Melanie Meersch +13 more
TL;DR: Among high-risk patients undergoing cardiac surgery, remote ischemic preconditioning significantly reduced the rate of acute kidney injury and use of renal replacement therapy and the need for renal replacement Therapy.