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Melanie Meersch

Researcher at University of Münster

Publications -  74
Citations -  4337

Melanie Meersch is an academic researcher from University of Münster. The author has contributed to research in topics: Acute kidney injury & Medicine. The author has an hindex of 17, co-authored 52 publications receiving 2922 citations.

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Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury: The ELAIN Randomized Clinical Trial

TL;DR: To determine whether early initiation of RRT in patients who are critically ill with AKI reduces 90-day all-cause mortality, a single-center randomized clinical trial of 231 critically ill patients with KDIGO stage 2 found that more patients in the early group recovered renal function by day 90.
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Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial

TL;DR: In this article, the efficacy of an implementation of the Kidney Disease Improving Global Outcomes (KDIGO) guidelines to prevent cardiac surgery-associated acute kidney injury (AKI) in high risk patients defined by renal biomarkers was evaluated.
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Erratum to: Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial.

TL;DR: An implementation of the KDIGO guidelines compared with standard care reduced the frequency and severity of AKI after cardiac surgery in high risk patients.
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Urinary TIMP-2 and IGFBP7 as Early Biomarkers of Acute Kidney Injury and Renal Recovery following Cardiac Surgery

TL;DR: Urinary [TIMP-2]*[IGFBP7] serves as a sensitive and specific biomarker to predict AKI early after cardiac surgery and to predict renal recovery in patients who developed AKI.
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Effect of remote ischemic preconditioning on kidney injury among high-risk patients undergoing cardiac surgery: a randomized clinical trial.

TL;DR: Among high-risk patients undergoing cardiac surgery, remote ischemic preconditioning significantly reduced the rate of acute kidney injury and use of renal replacement therapy and the need for renal replacement Therapy.