M
Melisa Beatriz Nicoud
Researcher at National Scientific and Technical Research Council
Publications - 12
Citations - 243
Melisa Beatriz Nicoud is an academic researcher from National Scientific and Technical Research Council. The author has contributed to research in topics: Histamine H4 receptor & Histamine. The author has an hindex of 7, co-authored 12 publications receiving 129 citations. Previous affiliations of Melisa Beatriz Nicoud include Pontifical Catholic University of Argentina & University of Buenos Aires.
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Journal ArticleDOI
Histamine receptors and cancer pharmacology: an update.
TL;DR: Finding show the pivotal role of H4 receptors in the development and progression of many types of cancers, and considering its immunomodulatory properties, the H4 receptor appears to be the most promising molecular therapeutic target for cancer treatment within the histamine receptor family.
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Selective cytoprotective effect of histamine on doxorubicin-induced hepatic and cardiac toxicity in animal models
Diego José Martinel Lamas,Diego José Martinel Lamas,Melisa Beatriz Nicoud,Helena Andrea Sterle,Eliana Carabajal,Fiorella Carla Tesan,Juan Carlos Perazzo,Graciela Cremaschi,Graciela Cremaschi,Elena Rivera,Vanina Araceli Medina,Vanina Araceli Medina +11 more
TL;DR: Preclinical evidence is provided indicating that histamine could be a promising candidate as a selective cytoprotective agent for the treatment of Dox-induced cardiac and hepatic toxicity, and encourage the translation to clinical practice.
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Immunomodulatory role of histamine H4 receptor in breast cancer.
Helena Andrea Sterle,Melisa Beatriz Nicoud,Melisa Beatriz Nicoud,Noelia Andrea Massari,Mónica A. Delgado,María Verónica Herrero Ducloux,Graciela Cremaschi,Graciela Cremaschi,Vanina Araceli Medina,Vanina Araceli Medina +9 more
TL;DR: This is the first report that demonstrates the participation of H4R in antitumour immunity, suggesting that H 4R could be a target for cancer treatment.
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Pathophysiological Role of Histamine H4 Receptor in Cancer: Therapeutic Implications.
TL;DR: Current knowledge in H 4R’s pharmacology and in the clinical use of H4R ligands are summarized before focusing on recent data reporting the expression of H3R and its pathophysiological role in cancer, representing a potential molecular target for cancer therapeutics.
Journal ArticleDOI
Histamine therapeutic efficacy in metastatic melanoma: Role of histamine H4 receptor agonists and opportunity for combination with radiation.
Noelia Andrea Massari,Noelia Andrea Massari,Melisa Beatriz Nicoud,Melisa Beatriz Nicoud,Lorena Andrea Sambuco,Graciela Cricco,Diego José Martinel Lamas,Diego José Martinel Lamas,María Verónica Herrero Ducloux,Horacio Alejandro Blanco,Elena Rivera,Vanina Araceli Medina,Vanina Araceli Medina +12 more
TL;DR: Medina et al. as discussed by the authors investigated the role of H 4 R in melanoma proliferation and assessed in vivo the therapeutic efficacy of histamine, clozapine and JNJ28610244 in a preclinical metastatic model of melanoma.