N
Noelia Andrea Massari
Researcher at University of Buenos Aires
Publications - 9
Citations - 316
Noelia Andrea Massari is an academic researcher from University of Buenos Aires. The author has contributed to research in topics: Histamine & Histamine H4 receptor. The author has an hindex of 9, co-authored 9 publications receiving 275 citations. Previous affiliations of Noelia Andrea Massari include National University of Patagonia San Juan Bosco.
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Journal ArticleDOI
The role of histamine in human mammary carcinogenesis: H3 and H4 receptors as potential therapeutic targets for breast cancer treatment.
Vanina Araceli Medina,Máximo Croci,Ernesto Crescenti,Nora Mohamad,Francisca Sánchez-Jiménez,Noelia Andrea Massari,Mariel Núñez,Graciela Cricco,G. Martín,Rosa Bergoc,Elena Rivera +10 more
TL;DR: The expression of histamine H3 (H3R) and H4 (H4R) receptors and their association with proliferating cell nuclear antigen (PCNA), histidine decarboxylase (HDC) and histamine content were explored in mammary biopsies and whether H3R and H 4R were implicated in the biological responses triggered by histamine in MDA-MB-231 breast cancer cells was investigated.
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Role of histamine H4 receptor in breast cancer cell proliferation.
Vanina Araceli Medina,Pablo G. Brenzoni,Diego José Martinel Lamas,Noelia Andrea Massari,Carolina Mondillo,Mariel Núñez,Omar Pedro Pignataro,Elena Rivera +7 more
TL;DR: It is concluded that H4R is functionally expressed in human breast cancer cell lines, exhibiting a key role in histamine-mediated biological processes such as cell proliferation, senescence and apoptosis.
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Therapeutic potential of histamine H4 receptor agonists in triple-negative human breast cancer experimental model
Diego José Martinel Lamas,Máximo Croci,Eliana Carabajal,Ernesto Crescenti,Lorena Andrea Sambuco,Noelia Andrea Massari,Rosa Bergoc,Elena Rivera,Vanina Araceli Medina,Vanina Araceli Medina +9 more
TL;DR: The aim of this work was to evaluate the effects of H4R ligands on the survival, tumour growth rate and metastatic capacity of breast cancer in an experimental model.
Journal ArticleDOI
Mechanisms underlying the radioprotective effect of histamine on small intestine.
Vanina Araceli Medina,Máximo Croci,Nora Mohamad,Noelia Andrea Massari,Gloria B. Garbarino,Graciela Cricco,Mariel Núñez,G. Martín,Ernesto Crescenti,Rosa Bergoc,Elena Rivera +10 more
TL;DR: Histamine prevents radiation-induced toxicity by increasing proliferation of damaged intestinal mucosa and suppressing apoptosis that was associated with an increase in SOD and Catalase levels.
Journal ArticleDOI
Antitumor activity of histamine and clozapine in a mouse experimental model of human melanoma.
Noelia Andrea Massari,Vanina Araceli Medina,Vanina Araceli Medina,Graciela Cricco,Diego José Martinel Lamas,Lorena Andrea Sambuco,Romina Pagotto,Clara Ventura,Pablo Juan Ciraolo,Omar Pedro Pignataro,Rosa Bergoc,Rosa Bergoc,Elena Rivera +12 more
TL;DR: In vivo studies show that HA and CLZ significantly increased median survival and decreased tumor volume on human melanoma, suggesting the therapeutic potential of these compounds for the treatment of malignant melanoma.