Melissa K. Andrew

TL;DR: The phenotypic definition of frailty, which offers ready clinical operationalization, discriminates broad levels of risk but requires additional clinical translation, but allows the risk of adverse outcomes to be defined more precisely.

TL;DR: A scoping review of interventions and international policies designed to prevent or reduce the level of frailty in community-dwelling older adults showed that the physical activity interventions (all types and combinations), and prehabilitation included the physical activities combined with nutrition, and the CGA studies had mixed findings.

TL;DR: A meaningful survival gradient across quartiles of social vulnerability is identified, and although women had better survival than men, survival for women with high social vulnerability was equivalent to that of men with low vulnerability.

TL;DR: A cross-sectional analysis of data from participants of the Rush Memory and Aging Project, a clinical-pathological cohort study of older adults without known dementia at baseline, found that frailty is related to both odds of Alzheimer's dementia and disease expression and has implications for clinical management.

TL;DR: To assess how individual socioeconomic status and neighborhood deprivation affect frailty, data are collected on household finances, diet, and physical activity in urban areas over a 10-year period.