M
Melissa Spacek
Researcher at University of North Carolina at Chapel Hill
Publications - 16
Citations - 831
Melissa Spacek is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Barrett's esophagus & Dysplasia. The author has an hindex of 11, co-authored 16 publications receiving 770 citations.
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Journal ArticleDOI
Randomised clinical trial: high-dose acid suppression for chronic cough – a double-blind, placebo-controlled study
Nicholas J. Shaheen,Seth D. Crockett,Stephanie D. Bright,Ryan D. Madanick,Robert A. Buckmire,Marion E. Couch,Evan S. Dellon,Joseph A. Galanko,Ginny Sharpless,Douglas R. Morgan,Melissa Spacek,Paris Heidt-Davis,David C. Henke +12 more
TL;DR: Aliment Pharmacol Ther 2011; 33: 225–234
Journal ArticleDOI
Safety and efficacy of endoscopic mucosal therapy with radiofrequency ablation for patients with neoplastic Barrett's esophagus.
William J. Bulsiewicz,Hannah P. Kim,Evan S. Dellon,Cary C. Cotton,Sarina Pasricha,Ryan D. Madanick,Melissa Spacek,Susan Bream,Xiaoxin Chen,Roy C. Orlando,Nicholas J. Shaheen +10 more
TL;DR: RFA is highly effective and safe for treatment of BE with dysplasia or early stage cancer and incomplete healing between treatment sessions was associated with incomplete EIM, and strictures were the most common complications.
Journal ArticleDOI
Intestinal metaplasia recurs infrequently in patients successfully treated for Barrett's esophagus with radiofrequency ablation.
Eric S. Orman,Hannah P. Kim,William J. Bulsiewicz,Cary C. Cotton,Evan S. Dellon,Melissa Spacek,Xiaoxin Chen,Ryan D. Madanick,Sarina Pasricha,Nicholas J. Shaheen +9 more
TL;DR: In patients with BE and dysplasia or early cancer who achieved CE-IM, BE recurred in ∼5%/year, and subjects undergoing RFA for dysplastic BE should be retained in endoscopic surveillance.
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Feasibility, safety, acceptability, and yield of office-based, screening transnasal esophagoscopy (with video).
Anne F. Peery,Toshitaka Hoppo,Katherine S. Garman,Katherine S. Garman,Evan S. Dellon,Norma Daugherty,Susan Bream,Alejandro F. Sanz,Jon M. Davison,Melissa Spacek,Diane Connors,Ashley L. Faulx,Amitabh Chak,James D. Luketich,Nicholas J. Shaheen,Blair A. Jobe +15 more
TL;DR: Unsedated transnasal esophagoscopy is a feasible, safe, and well-tolerated method to screen for esophageal disease in a primary care population.
Journal ArticleDOI
Single and Multiple Dose Pharmacokinetics of Maraviroc in Saliva, Semen, and Rectal Tissue of Healthy HIV-Negative Men
Kevin C. Brown,Kristine B. Patterson,Stephanie Malone,Nicholas J. Shaheen,Heather M.A. Prince,Julie B. Dumond,Melissa Spacek,Paris Heidt,Myron S. Cohen,Angela D. M. Kashuba +9 more
TL;DR: Saliva correlation with BP suggests that this may be useful for monitoring adherence in HIV-negative men, and more pharmacologically available maraviroc was found in SP than BP.