M
Meng Wu
Researcher at Huazhong University of Science and Technology
Publications - 42
Citations - 586
Meng Wu is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 11, co-authored 25 publications receiving 265 citations. Previous affiliations of Meng Wu include Chinese Ministry of Education.
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Journal ArticleDOI
Are sirtuins markers of ovarian aging
TL;DR: Results indicate that SIRT1, SIRT3 and SIRT6 are closely related to ovarian reserve, and suggest that these sirtuins may be markers of ovarian aging.
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Long-Term Moderate Oxidative Stress Decreased Ovarian Reproductive Function by Reducing Follicle Quality and Progesterone Production.
Liangyan Shi,Jinjin Zhang,Zhiwen Lai,Yong Tian,Li Fang,Meng Wu,Jiaqiang Xiong,Xian Qin,Aiyue Luo,Shixuan Wang +9 more
TL;DR: The findings suggest that the decreased female reproductive function caused by long-term moderate oxidative damage may be due to a decrease in follicle quality and progesterone production.
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Red blood cell membrane-camouflaged nanoparticles loaded with AIEgen and Poly(I : C) for enhanced tumoral photodynamic-immunotherapy.
Jun Dai,Meng Wu,Quan Wang,Siyang Ding,Xiaoqi Dong,Liru Xue,Qingqing Zhu,Jian Zhou,Fan Xia,Shixuan Wang,Yuning Hong +10 more
TL;DR: This strategy combines the PDT properties of the AIE-active polyelectrolyte and immunotherapy properties of Poly(I : C) to achieve synergistic activation of the immune system for anti-tumor activity, providing a novel strategy for tumor treatment.
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Resveratrol alleviates chemotherapy-induced oogonial stem cell apoptosis and ovarian aging in mice.
Meng Wu,Lingwei Ma,Liru Xue,Wenlei Ye,Zhiyong Lu,Xiang Li,Yan Jin,Xian Qin,Dan Chen,Weicheng Tang,Yingying Chen,Zixin Hong,Jinjin Zhang,Aiyue Luo,Shixuan Wang +14 more
TL;DR: Resveratrol exerted a dose-dependent effect on oogonial stem cells and attenuated H2O2-induced cytotoxicity and oxidative stress injury by activating Nrf2 in vitro and could be of a potential therapeutic drug used to prevent chemotherapy-induced ovarian aging.
Journal ArticleDOI
Can ovarian aging be delayed by pharmacological strategies
Jinjin Zhang,Qian Chen,Dingfu Du,Tong Wu,Jingyi Wen,Meng Wu,Yan Zhang,Wei Yan,Su Zhou,Yan Li,Yan Jin,Aiyue Luo,Shixuan Wang +12 more
TL;DR: This review is attempted to discuss recent advances in the area of anti-ovarian aging pharmacology and to offer new insights into the better understanding of molecular mechanisms underlying ovarian aging, which might be informative for future prevention and treatment of ovarian aging and its related diseases.