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Aiyue Luo

Researcher at Huazhong University of Science and Technology

Publications -  48
Citations -  1054

Aiyue Luo is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Ovarian reserve & Biology. The author has an hindex of 18, co-authored 41 publications receiving 753 citations.

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Expression Patterns and Regulatory Functions of MicroRNAs During the Initiation of Primordial Follicle Development in the Neonatal Mouse Ovary

TL;DR: The data suggest that miRNAs and the signaling pathways they modulate are involved in the initiation of primordial follicle development, and miR-145 targets Tgfbr2 to regulate the Initiation of Primordial follicles development and maintain primordialowlicle quiescence.
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Circular RNA expression profiling of human granulosa cells during maternal aging reveals novel transcripts associated with assisted reproductive technology outcomes.

TL;DR: Bioinformatics analysis revealed that both circRNAs were potentially involved in glucose metabolism, mitotic cell cycle, and ovarian steroidogenesis, and might be potential indicators of compromised follicular micro-environment which could be used to predict IVF prognosis, and improve female infertility management.
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Antisense targeting human papillomavirus type 16 E6 and E7 genes contributes to apoptosis and senescence in SiHa cervical carcinoma cells.

TL;DR: It is demonstrated that reduction of E6 and E7 expression is sufficient to induce SiHa cells to undergo apoptosis and senescence and suggest that transfection of cervical cancer cells with HPV-16 E6and E7 antisense RNA is a potential approach to treat HPV- 16-positive cervical cancers.
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Are sirtuins markers of ovarian aging

TL;DR: Results indicate that SIRT1, SIRT3 and SIRT6 are closely related to ovarian reserve, and suggest that these sirtuins may be markers of ovarian aging.
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Long-Term Moderate Oxidative Stress Decreased Ovarian Reproductive Function by Reducing Follicle Quality and Progesterone Production.

TL;DR: The findings suggest that the decreased female reproductive function caused by long-term moderate oxidative damage may be due to a decrease in follicle quality and progesterone production.