M
Mengna Gao
Researcher at Xiamen University
Publications - 12
Citations - 212
Mengna Gao is an academic researcher from Xiamen University. The author has contributed to research in topics: Spect imaging & Folate receptor. The author has an hindex of 9, co-authored 11 publications receiving 174 citations.
Papers
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Journal ArticleDOI
Superfluorinated PEI Derivative Coupled with (99m) Tc for ASGPR Targeted (19) F MRI/SPECT/PA Tri-Modality Imaging.
Zhide Guo,Mengna Gao,Manli Song,Yesen Li,Deliang Zhang,Duo Xu,Linyi You,Liangliang Wang,Rongqiang Zhuang,Xinhui Su,Ting Liu,Jin Du,Xianzhong Zhang +12 more
TL;DR: Fluorinated polyethylenimine derivative labeled with radionuclide (99m) Tc is developed as a multifunctional imaging agent with good asialoglycoprotein receptors (ASGPR)-targeting ability and has the potential to detect hepatic diseases and to assess liver function.
Journal ArticleDOI
Highly specific C–C bond cleavage induced FRET fluorescence for in vivo biological nitric oxide imaging
Hua Li,Deliang Zhang,Mengna Gao,Lumei Huang,Longguang Tang,Zijing Li,Xiaoyuan Chen,Xianzhong Zhang +7 more
TL;DR: A novel FRET fluorescence “off–on” system based on the highly specific, sensitive and effective C–C bond cleavage of certain dihydropyridine derivatives was reported for real-time quantitative imaging of nitric oxide (NO).
Journal ArticleDOI
Desmin- and vimentin-mediated hepatic stellate cell-targeting radiotracer 99mTc-GlcNAc-PEI for liver fibrosis imaging with SPECT.
Deliang Zhang,Rongqiang Zhuang,Zhide Guo,Mengna Gao,Lumei Huang,Linyi You,Pu Zhang,Jindian Li,Xinhui Su,Hua Wu,Xiaoyuan Chen,Xianzhong Zhang +11 more
TL;DR: 99mTc-GlcNAc-PEI SPECT/CT was useful in assessing liver fibrosis and monitoring the treatment response and was a hydrophilic compound with high radiochemical purity (>98%) and good stability.
Journal ArticleDOI
Synthesis and Evaluation of (99m)Tc-Labeled Dimeric Folic Acid for FR-Targeting.
Zhide Guo,Mengna Gao,Manli Song,Changrong Shi,Pu Zhang,Duo Xu,Linyi You,Rongqiang Zhuang,Xinhui Su,Ting Liu,Jin Du,Xianzhong Zhang +11 more
TL;DR: Based on the results, this new radiolabeled dimeric FA tracer might be a promising candidate for FR-targeting imaging with high affinity and selectivity.
Journal ArticleDOI
Simplified quantification method for in vivo SPECT/CT imaging of asialoglycoprotein receptor with (99m)Tc-p(VLA-co-VNI) to assess and stage hepatic fibrosis in mice.
Deliang Zhang,Zhide Guo,Pu Zhang,Yesen Li,Xinhui Su,Linyi You,Mengna Gao,Chang Liu,Hua Wu,Xianzhong Zhang +9 more
TL;DR: SPECT imaging with 99mTc-p(VLA-co-VNI) is useful in evaluating and staging liver fibrosis in vivo and ASGP-R expression decreased in carbon tetrachloride-induced mouse model.