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Deliang Zhang

Researcher at Xiamen University

Publications -  22
Citations -  280

Deliang Zhang is an academic researcher from Xiamen University. The author has contributed to research in topics: Spect imaging & Chemistry. The author has an hindex of 8, co-authored 17 publications receiving 195 citations.

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Modularized peptides modified HBc virus-like particles for encapsulation and tumor-targeted delivery of doxorubicin.

TL;DR: It is demonstrated that the recombinant HBc-based VLPs could participate in self-assembly of monodisperse nanoparticles with well-defined morphology, and DOX can be packaged into VLNPs without any chemical modification.
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Superfluorinated PEI Derivative Coupled with (99m) Tc for ASGPR Targeted (19) F MRI/SPECT/PA Tri-Modality Imaging.

TL;DR: Fluorinated polyethylenimine derivative labeled with radionuclide (99m) Tc is developed as a multifunctional imaging agent with good asialoglycoprotein receptors (ASGPR)-targeting ability and has the potential to detect hepatic diseases and to assess liver function.
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Highly specific C–C bond cleavage induced FRET fluorescence for in vivo biological nitric oxide imaging

TL;DR: A novel FRET fluorescence “off–on” system based on the highly specific, sensitive and effective C–C bond cleavage of certain dihydropyridine derivatives was reported for real-time quantitative imaging of nitric oxide (NO).
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Desmin- and vimentin-mediated hepatic stellate cell-targeting radiotracer 99mTc-GlcNAc-PEI for liver fibrosis imaging with SPECT.

TL;DR: 99mTc-GlcNAc-PEI SPECT/CT was useful in assessing liver fibrosis and monitoring the treatment response and was a hydrophilic compound with high radiochemical purity (>98%) and good stability.
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Simplified quantification method for in vivo SPECT/CT imaging of asialoglycoprotein receptor with (99m)Tc-p(VLA-co-VNI) to assess and stage hepatic fibrosis in mice.

TL;DR: SPECT imaging with 99mTc-p(VLA-co-VNI) is useful in evaluating and staging liver fibrosis in vivo and ASGP-R expression decreased in carbon tetrachloride-induced mouse model.