M
Michael Coverstone
Researcher at Duke University
Publications - 2
Citations - 233
Michael Coverstone is an academic researcher from Duke University. The author has contributed to research in topics: Cyclase & Alprenolol. The author has an hindex of 2, co-authored 2 publications receiving 232 citations.
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Stereospecific (3H)(minus)-alprenolol binding sites, beta-adrenergic receptors and adenylate cyclase.
TL;DR: The binding of [ 3 H]-alprenolol (a potent β-adrenergic antagonist) to sites in frog erythrocyte membranes has been studied by a centrifugal assay as discussed by the authors.
Identification of Adenylate Cyclase-coupled fi -Adrenergic Receptors in Frog Erythrocytes with (-) -( 311) Alprenolol"
TL;DR: Alprenolol, a potent, competitive @- adrenergic antagonist labeled to high specific activity with tritium, has been used to identify binding sites in frog erythrocyte membranes having many of the characteristics to be expected of the P-adrenergic receptors which are linked to adenylate cyclase in these membranes.