M
Michael D. Young
Researcher at University of Queensland
Publications - 2
Citations - 292
Michael D. Young is an academic researcher from University of Queensland. The author has contributed to research in topics: Phosphorylation & Pilus. The author has an hindex of 2, co-authored 2 publications receiving 264 citations.
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Journal ArticleDOI
Characterization of a complex chemosensory signal transduction system which controls twitching motility in Pseudomonas aeruginosa
Cynthia B. Whitchurch,Andrew J. Leech,Michael D. Young,Derek Kennedy,Derek Kennedy,Jennifer L Sargent,Jacob J. Bertrand,A Semmler,Albert S. Mellick,Paul R. Martin,Richard A. Alm,Matthew Hobbs,Scott A. Beatson,Bixing Huang,Lam Nguyen,James C. Commolli,Joanne N. Engel,Aldis Darzins,John S. Mattick +18 more
TL;DR: It is shown that the Chp chemosensory system controls twitching motility and type IV pili biogenesis through control of pili assembly and/or retraction as well as expression of the pilin subunit gene pilA, required for full virulence in a mouse model of acute pneumonia.
Journal ArticleDOI
Phosphorylation of the Pseudomonas aeruginosa Response Regulator AlgR Is Essential for Type IV Fimbria-Mediated Twitching Motility
Cynthia B. Whitchurch,Tatiana E Erova,Jacqui A Emery,Jennifer L Sargent,Jonathon M Harris,Analese B T Semmler,Michael D. Young,John S. Mattick,Daniel J. Wozniak +8 more
TL;DR: Findings indicate that phosphorylation of AlgR most likely occurs at aspartate 54 and that aspartates 54 and as partate 85 of Al gR are required for the control of the molecular events governing fimbrial biogenesis, twitching motility, and biofilm formation in P. aeruginosa.