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Albert S. Mellick
Researcher at University of New South Wales
Publications - 34
Citations - 2317
Albert S. Mellick is an academic researcher from University of New South Wales. The author has contributed to research in topics: Breast cancer & Progenitor cell. The author has an hindex of 18, co-authored 31 publications receiving 2171 citations. Previous affiliations of Albert S. Mellick include University of Sydney & University of Queensland.
Papers
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Journal ArticleDOI
Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis
Dingcheng Gao,Daniel J. Nolan,Albert S. Mellick,Kathryn Bambino,Kevin McDonnell,Vivek Mittal +5 more
TL;DR: It is shown that tumors induce expression of the transcription factor Id1 in the EPCs and that suppression of Id1 after metastatic colonization blocked EPC mobilization, caused angiogenesis inhibition, impaired pulmonary macrometastases, and increased survival of tumor-bearing animals.
Journal ArticleDOI
Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization
Daniel J. Nolan,Daniel J. Nolan,Alessia Ciarrocchi,Albert S. Mellick,Jaspreet Singh Jaggi,Kathryn Bambino,Sunita Gupta,Emily Heikamp,Michael R. McDevitt,David A. Scheinberg,Robert Benezra,Vivek Mittal +11 more
TL;DR: It is demonstrated that early tumors recruit BM- derived EPCs that differentiate into mature BM-derived endothelial cells (ECs) and luminally incorporate into a subset of sprouting tumor neovessels, which accounts for purported differences in previously published reports.
Journal ArticleDOI
Characterization of a complex chemosensory signal transduction system which controls twitching motility in Pseudomonas aeruginosa
Cynthia B. Whitchurch,Andrew J. Leech,Michael D. Young,Derek Kennedy,Derek Kennedy,Jennifer L Sargent,Jacob J. Bertrand,A Semmler,Albert S. Mellick,Paul R. Martin,Richard A. Alm,Matthew Hobbs,Scott A. Beatson,Bixing Huang,Lam Nguyen,James C. Commolli,Joanne N. Engel,Aldis Darzins,John S. Mattick +18 more
TL;DR: It is shown that the Chp chemosensory system controls twitching motility and type IV pili biogenesis through control of pili assembly and/or retraction as well as expression of the pilin subunit gene pilA, required for full virulence in a mouse model of acute pneumonia.
Journal ArticleDOI
Quantitative and qualitative changes in gene expression patterns characterize the activity of plaques in multiple sclerosis
Lotti Tajouri,Albert S. Mellick,Kevin J. Ashton,Anthony E.G. Tannenberg,Rashed M. Nagra,Wallace W. Tourtellotte,Lyn R. Griffiths +6 more
TL;DR: In this paper, RNA from MS chronic active and acute lesions was extracted, and compared with patient matched normal white matter by fluorescent cDNA microarray hybridization analysis, which resulted in the identification of 139 genes that were differentially regulated in MS plaque tissue compared to normal tissue.
Book
Lab Ref: A Handbook of Recipes, Reagents, and Other Reference Tools for Use at the Bench
TL;DR: This paper presents Quantitative Methods in Protein Analysis for Proteomics Extraction of Proteins Advanced Protocols in Identifying Protein-Protein Interactions forproteomics, and some Buffers and Solutions.