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Michael E. Sughrue

Researcher at University of Oklahoma Health Sciences Center

Publications -  320
Citations -  8960

Michael E. Sughrue is an academic researcher from University of Oklahoma Health Sciences Center. The author has contributed to research in topics: Medicine & Meningioma. The author has an hindex of 48, co-authored 284 publications receiving 7058 citations. Previous affiliations of Michael E. Sughrue include University of Oklahoma & University of California, San Francisco.

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The relevance of Simpson Grade I and II resection in modern neurosurgical treatment of World Health Organization Grade I meningiomas.

TL;DR: The authors believe that these data reflect an evolution in the nature of meningioma surgery over the past 2 decades, and bring into question the relevance of using Simpson's grading system as the sole predictor of recurrence.
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Cancer and the complement cascade

TL;DR: A new way of thinking about the role of complement proteins in neoplasia is suggested, given that the traditionally held functions for the complement system include innate immunity and cancer defense.
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Complement Component C3 Mediates Inflammatory Injury Following Focal Cerebral Ischemia

TL;DR: C3 activation is established as the key constituent in complement-related inflammatory tissue injury following stroke and a C3a anaphylatoxin-mediated mechanism is suggested.
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Anatomic Location Is a Risk Factor for Atypical and Malignant Meningiomas

TL;DR: A large series of patients are reviewed to determine risk factors for higher‐grade pathology, with particular interest paid to tumor location, for brain tumors after surgery and/or external irradiation.
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A meta-analysis of predictors of seizure freedom in the surgical management of focal cortical dysplasia.

TL;DR: Using a large population cohort pooled from the published literature, an analysis identified important factors that are prognostic in patients with epilepsy due to FCD-diagnostic imaging and resection provide modalities through which improvements in the impact of FCD can be effected.