M
Michael I. Miller
Researcher at Johns Hopkins University
Publications - 640
Citations - 38471
Michael I. Miller is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Large deformation diffeomorphic metric mapping & Computational anatomy. The author has an hindex of 92, co-authored 599 publications receiving 34915 citations. Previous affiliations of Michael I. Miller include University of Tennessee & Discovery Institute.
Papers
More filters
Patent
Method and apparatus for processing images with regions representing target objects
TL;DR: In this article, the first and second images are registered using a first transform component that filters one or more data elements in the second image that are contained in the identified region, and a second transform component, which includes the image data elements representing a target object.
Journal ArticleDOI
Brain segmentation and the generation of cortical surfaces.
Mukta Joshi,Jing Cui,Keith W. Doolittle,Sarang Joshi,David C. Van Essen,Lei Wang,Michael I. Miller +6 more
TL;DR: A system that allows a user to start with a brain volume, obtained by modalities such as MRI or cryosection, and constructs a complete digital representation of the cortical surface, and the generation of cortical surfaces from the segmentations is developed.
Journal ArticleDOI
Parallel transport in diffeomorphisms distinguishes the time-dependent pattern of hippocampal surface deformation due to healthy aging and the dementia of the Alzheimer's type
TL;DR: Use of parallel transport in diffeomorphisms under the large deformation diffeomorphic metric mapping framework to translate within-subject deformation of the hippocampal surface as represented in the MR images between the two time points in a global template coordinate system was used.
Journal ArticleDOI
Relationship of medial temporal lobe atrophy, APOE genotype, and cognitive reserve in preclinical Alzheimer's disease
Anja Soldan,Corinne Pettigrew,Yi Lu,Mei Cheng Wang,Ola A. Selnes,Marilyn Albert,Timothy Brown,J. Tilak Ratnanather,Laurent Younes,Michael I. Miller +9 more
TL;DR: MRI measures of medial temporal atrophy, ApoE‐ɛ4 genotype, and the protective effects of higher CR all predict the time to onset of symptoms associated with MCI in a largely independent, additive manner during the preclinical phase of Alzheimer's disease.
Journal ArticleDOI
Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images.
Jiangyang Zhang,Qi Peng,Qing Li,Neda Jahanshad,Zhipeng Hou,Mali Jiang,Naoki Masuda,Douglas R. Langbehn,Michael I. Miller,Michael I. Miller,Susumu Mori,Susumu Mori,Christopher A. Ross,Wenzhen Duan +13 more
TL;DR: This is the first report of longitudinal characterization of brain atrophy in a mouse model of Huntington's disease by using automatic morphological analysis, and comparison between ex vivo and in vivo MRI suggests that the ex vivo end-point measurement of brain morphology is also a valid approach except for the morphology of the ventricles.