M
Michael J. Natan
Researcher at Pennsylvania State University
Publications - 93
Citations - 19159
Michael J. Natan is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Nanoparticle & Surface plasmon resonance. The author has an hindex of 51, co-authored 89 publications receiving 18487 citations. Previous affiliations of Michael J. Natan include North Carolina State University & Massachusetts Institute of Technology.
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Journal ArticleDOI
Preparation and Characterization of Au Colloid Monolayers
TL;DR: In this article, the design and initial characterization of two-dimensional arrays of colloidal Au particles are reported, which are prepared by self-assembly of 12 nm diameter colloidal particles onto immobilized polymers having pendant functional groups with high affinity for Au (i.e., CN, SH, and NH 2 ).
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Submicrometer metallic barcodes.
Sheila R. Nicewarner-Peña,R. Griffith Freeman,Brian D. Reiss,Lin He,David J. Peña,Ian D. Walton,Remy Cromer,Christine D. Keating,Michael J. Natan +8 more
TL;DR: The differential reflectivity of adjacent stripes enables identification of the striping patterns by conventional light microscopy, and this readout mechanism does not interfere with the use of fluorescence for detection of analytes bound to particles by affinity capture, as demonstrated by DNA and protein bioassays.
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Self-Assembled Metal Colloid Monolayers: An Approach to SERS Substrates.
R. G. Freeman,Katherine C. Grabar,K J Allison,Robin M. Bright,J A Davis,A P Guthrie,Michael B. Hommer,Michael A. Jackson,Patrick C. Smith,Daniel G. Walter,Michael J. Natan +10 more
TL;DR: On conducting substrates, colloid monolayers are electrochemically addressable and behave like a collection of closely spaced microelectrodes, which suggest a widespread use for metal colloid-based substrates.
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Seeding of Colloidal Au Nanoparticle Solutions. 2. Improved Control of Particle Size and Shape
TL;DR: In this article, the surface of preformed 12-nm-diameter Au nanoparticles is reduced by boiling sodium citrate, producing particles highly uniform in size and shape, and a similar procedure, utilizing the reductant NH2OH at room temperature, produces two populations of particles.
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Colloidal Au-Enhanced Surface Plasmon Resonance for Ultrasensitive Detection of DNA Hybridization
Lin He,Michael D. Musick,Sheila R. Nicewarner,Frank Salinas,Stephen J. Benkovic,Michael J. Natan,Christine D. Keating +6 more
TL;DR: A new approach to ultrasensitive detection of DNA hybridization based on nanoparticle-amplified surface plasmon resonance (SPR) is described, with a greater than 10-fold increase in angle shift and a more than 1000-fold improvement in sensitivity for the target oligonucleotide as compared to the unamplify binding event.