M
Michael J. Wannemuehler
Researcher at Iowa State University
Publications - 173
Citations - 6052
Michael J. Wannemuehler is an academic researcher from Iowa State University. The author has contributed to research in topics: Antigen & Immune system. The author has an hindex of 43, co-authored 162 publications receiving 5365 citations. Previous affiliations of Michael J. Wannemuehler include University of Minnesota.
Papers
More filters
Journal ArticleDOI
Vaccine adjuvants: current challenges and future approaches.
Jennifer H. Wilson-Welder,Maria P. Torres,Matt J. Kipper,Surya K. Mallapragada,Michael J. Wannemuehler,Balaji Narasimhan +5 more
TL;DR: A comprehensive discussion is presented of current vaccine adjuvants, their effects on the induction of immune responses, and vaccine adjUVants that have shown promise in recent literature.
Journal Article
Lipopolysaccharide (LPS) regulation of the immune response: LPS converts germfree mice to sensitivity to oral tolerance induction.
Journal ArticleDOI
The Altered Schaedler Flora: Continued Applications of a Defined Murine Microbial Community.
Meghan Wymore Brand,Michael J. Wannemuehler,Gregory J. Phillips,Alexandra Proctor,Anne-Marie C. Overstreet,Albert E. Jergens,Roger P. Orcutt,James G. Fox +7 more
TL;DR: This review compiles highlights associated with the 37-year history of the altered Schaedler flora, including descriptions of its continued use in biomedical research to elucidate the complexities of host-microbiome interactions in health and disease.
Journal ArticleDOI
Mannose-functionalized "pathogen-like" polyanhydride nanoparticles target C-type lectin receptors on dendritic cells.
Brenda R. Carrillo-Conde,Eun-Ho Song,Ana Vianey Chavez-Santoscoy,Yashdeep Phanse,Amanda E. Ramer-Tait,Nicola L. B. Pohl,Michael J. Wannemuehler,Bryan H. Bellaire,Balaji Narasimhan +8 more
TL;DR: A novel approach to targeted antigen delivery is described by decorating the surface of polyanhydride nanoparticles with specific carbohydrates to provide "pathogen-like" properties that ensure nanoparticles engage C-type lectin receptors on DCs.
Journal ArticleDOI
Activation of innate immune responses in a pathogen-mimicking manner by amphiphilic polyanhydride nanoparticle adjuvants.
Latrisha K. Petersen,Amanda E. Ramer-Tait,Scott Broderick,Chang-Sun Kong,Bret D. Ulery,Krishna Rajan,Michael J. Wannemuehler,Balaji Narasimhan +7 more
TL;DR: The approach outlined herein demonstrates the ability to rationally design pathogen-mimicking nanoparticle adjuvants for use in next-generation vaccines against emerging and re-emerging diseases.