Michael Mallozzi

TL;DR: This work determined the roles of several B. anthracis orthologues of Bacillus subtilis coat protein genes in spore assembly and virulence and found that SpoIVA has a critical role in directing the assembly of the coat and exosporium to an area around the forespore.

TL;DR: Investigating the surface adhesive properties of Bacillus subtilis and Bacillus anthracis spores indicated that both species were monopolar with a preponderance of electron-donating potential and mutant spores missing outer layers had different surface thermodynamic and transport properties as compared to wild type spores.

TL;DR: It is suggested that at least some ExsFB-GFP and IunH-G FP resides in the region between the coat and the exosporium, called the interspace, which is similar to an inosine-uridine-preferring nucleoside hydrolase.

TL;DR: A revised model of exospora maturation and assembly is proposed and a novel role for the exosporium in germination is suggested, found that ExsK is not required for virulence in murine and guinea pig models but that it does inhibit germination.

TL;DR: This study provides direct evidence that B cell development in GALT may be driven by superantigen-like molecules, and furthermore, that bacterial spores modulate host immunity.